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| 카탈로그 번호 | HB196014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 설명 |
Anti-Human MYOG Polyclonal Antibody (HB196014) is a rabbit polyclonal antibody detecting MYOG in ELISA, IHC, WB. Suitable for Human, Mouse, Rat.
Highlights
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| 종 반응성 | Human, Mouse, Rat | ||||||||
| 응용 분야 | ELISA, IHC, WB | ||||||||
| 숙주 종 | Rabbit | ||||||||
| 클론성 | Polyclonal | ||||||||
| 이소타입 | IgG | ||||||||
| 면역원 | E. coli - derived recombinant Human MYOG (Leu66-Gln155). | ||||||||
| 타겟 | Myf-4, Myogenin, bHLHc3, BHLHC3, MYOG, MYF4, Myogenic factor 4, Class C basic helix-loop-helix protein 3 | ||||||||
| 정제 | Purified by antigen affinity column. | ||||||||
| 등록번호 | P15173 | ||||||||
| 형태 | Liquid | ||||||||
| 저장 완충액 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 배경 | Myogenin is a ~25 kDa protein. Acts as a transcriptional activator that promotes transcription of muscle-specific target genes and plays a role in muscle differentiation, cell cycle exit and muscle atrophy. Essential for the development of functional embryonic skeletal fiber muscle differentiation. However is dispensable for postnatal skeletal muscle growth; phosphorylation by CAMK2G inhibits its transcriptional activity in respons to muscle activity. Required for the recruitment of the FACT complex to muscle-specific promoter regions, thus promoting gene expression initiation. During terminal myoblast differentiation, plays a role as a strong activator of transcription at loci with an open chromatin structure previously initiated by MYOD1. | ||||||||
| 참고사항 | For research use only. |
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