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| 카탈로그 번호 | HW363013 | ||||
|---|---|---|---|---|---|
| 종 반응성 | Human | ||||
| 응용 분야 | ELISA | ||||
| 숙주 종 | Mouse | ||||
| 클론성 | Monoclonal | ||||
| 이소타입 | IgG2a, kappa | ||||
| 클론 ID | SAA1637 | ||||
| 타겟 | NAMPT, Pre-B-cell colony-enhancing factor 1, NAmPRTase, Pre-B cell-enhancing factor, Nicotinamide phosphoribosyltransferase, Visfatin, PBEF, PBEF1, Nampt | ||||
| 내독소 수준 | Please contact with the lab for this information. | ||||
| 순도 | >95% as determined by SDS-PAGE. | ||||
| 정제 | Protein A/G purified from cell culture supernatant. | ||||
| 등록번호 | P43490 | ||||
| RRID | Anti-Human NAMPT Antibody (SAA1637) (abinScience Cat# HW363013, RRID:AB_3727398) |
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| 형태 | Liquid | ||||
| 저장 완충액 | 0.01M PBS pH 7.4 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. | ||||
| 배경 | Nicotinamide phosphoribosyltransferase (NAMPT) is a ~55 kDa protein. Catalyzes the condensation of nicotinamide with 5-phosphoribosyl-1-pyrophosphate to yield nicotinamide mononucleotide, an intermediate in the biosynthesis of NAD. It is the rate limiting component in the mammalian NAD biosynthesis pathway. The secreted form behaves both as a cytokine with immunomodulating properties and an adipokine with anti-diabetic properties, it has no enzymatic activity, partly because of lack of activation by ATP, which has a low level in extracellular space and plasma. Plays a role in the modulation of circadian clock function. NAMPT-dependent oscillatory production of NAD regulates oscillation of clock target gene expression by releasing the core clock component: CLOCK-BMAL1 heterodimer from NAD-dependent SIRT1-mediated suppression. | ||||
| 참고사항 | For research use only. |
SDS-PAGE for Anti-Human NAMPT Antibody (SAA1637)
+86-027-65523339
중국 우한시 심둔사로 666번지 C동, 우한, 430206
