Anti-Human NASP Polyclonal Antibody (HC209014)

Name: Anti-Human NASP Polyclonal Antibody
Brand: abinScience
SKU: HC209014
Price: 168 USD
Availability: InStock

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100ug

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개요
이미지
참고 문헌
데이터시트
SDS

개요

카탈로그 번호

HC209014

설명

Anti-Human NASP Polyclonal Antibody (HC209014) is a rabbit polyclonal antibody detecting NASP. Suitable for Mouse, Human, and Rat.

Highlights

●Multi-Species — Cross-reactive for translational research.

종 반응성

Human, Mouse, Rat

응용 분야

ELISA, IHC, WB

숙주 종

Rabbit

클론성

Polyclonal

이소타입

IgG

면역원

E. coli - derived recombinant Human NASP (Gly513-Gly681).

타겟

NASP, Nuclear autoantigenic sperm protein

내독소 수준

Please contact with the lab for this information.

정제

Purified by antigen affinity column.

등록번호

P49321

형태

Liquid

저장 완충액

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

제품 사용 정보

응용 분야	희석
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

배경

Nuclear autoantigenic sperm protein (NASP) is a ~85 kDa protein. Component of the histone chaperone network. Binds and stabilizes histone H3-H4 not bound to chromatin to maintain a soluble reservoir and modulate degradation by chaperone-mediated autophagy. Required for DNA replication, normal cell cycle progression and cell proliferation. Forms a cytoplasmic complex with HSP90 and H1 linker histones and stimulates HSP90 ATPase activity. NASP and H1 histone are subsequently released from the complex and translocate to the nucleus where the histone is released for binding to DNA.

1. Cook, AJ. et al. (2011) Molecular cell 44, 918-27. PMID: 22195965

참고사항

For research use only

이미지

Western blot

Western blot analysis was performed using anti-NASP polyclonal antibody at 1ug/mL on various samples.
Lane 1: K562 cell lysate
Lane 2: 293T cell lysate
Lane 3: HL-60 cell lysate

참고 문헌

데이터시트

Anti-Human NASP Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

재조합 단백질

항체

어세이 키트

Anti-Human NASP Polyclonal Antibody (HC209014)

개요

이미지

참고 문헌

데이터시트

SDS