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| 카탈로그 번호 | HC485014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 설명 |
Anti-Human NCAPH Polyclonal Antibody (HC485014) is a rabbit polyclonal antibody detecting NCAPH in ELISA, IHC, WB. Suitable for Human.
Highlights
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| 종 반응성 | Human | ||||||||
| 응용 분야 | ELISA, IHC, WB | ||||||||
| 숙주 종 | Rabbit | ||||||||
| 클론성 | Polyclonal | ||||||||
| 이소타입 | IgG | ||||||||
| 면역원 | E. coli - derived recombinant Human NCAPH (Glu471-Pro526). | ||||||||
| 타겟 | CAPH, BRRN1, hCAP-H, Barren homolog protein 1, XCAP-H homolog, Non-SMC condensin I complex subunit H, BRRN, Chromosome-associated protein H, NCAPH, Condensin complex subunit 2, KIAA0074 | ||||||||
| 정제 | Purified by antigen affinity column. | ||||||||
| 등록번호 | Q15003 | ||||||||
| 형태 | Liquid | ||||||||
| 저장 완충액 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 배경 | Condensin complex subunit 2 (NCAPH) is a ~82 kDa protein. Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases. Early in neurogenesis, may play an essential role to ensure accurate mitotic chromosome condensation in neuron stem cells, ultimately affecting neuron pool and cortex size. 1. Kimura, K. et al. (2001) The Journal of biological chemistry 276, 5417-20. PMID: 11136719 2. Martin, CA. et al. (2016) Genes & development 30, 2158-2172. PMID: 27737959 | ||||||||
| 참고사항 | For research use only. |
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