

| 카탈로그 번호 | HD541014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 설명 |
Anti-Human NCOR1 Polyclonal Antibody (HD541014) is a rabbit polyclonal antibody detecting NCOR1. Suitable for Human.
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| 종 반응성 | Human, Mouse | ||||||||
| 응용 분야 | ELISA, IHC, WB | ||||||||
| 숙주 종 | Rabbit | ||||||||
| 클론성 | Polyclonal | ||||||||
| 이소타입 | IgG | ||||||||
| 면역원 | E. coli - derived recombinant Human NCOR1 (Met424-Gly500&Trp628-Pro690). | ||||||||
| 타겟 | KIAA1047, N-CoR, N-CoR1, NCOR1, Nuclear receptor corepressor 1 | ||||||||
| 내독소 수준 | Please contact with the lab for this information. | ||||||||
| 정제 | Purified by antigen affinity column. | ||||||||
| 등록번호 | O75376 | ||||||||
| 형태 | Liquid | ||||||||
| 저장 완충액 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 배경 | Nuclear receptor corepressor 1 (NCOR1) is a ~270 kDa protein. Mediates transcriptional repression by certain nuclear receptors. Part of a complex which promotes histone deacetylation and the formation of repressive chromatin structures which may impede the access of basal transcription factors. Participates in the transcriptional repressor activity produced by BCL6. Recruited by ZBTB7A to the androgen response elements/ARE on target genes, negatively regulates androgen receptor signaling and androgen-induced cell proliferation. Mediates the NR1D1-dependent repression and circadian regulation of TSHB expression. 1. Cui, J. et al. (2011) Cellular and molecular life sciences : CMLS 68, 1091-103. PMID: 20812024 | ||||||||
| 참고사항 | For research use only |

Lane 1: K562 cell lysate
Lane 2: NIH3T3 cell lysate
Lane 3: 293T cell lysate
Lane 4: Hela cell lysate


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