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| 카탈로그 번호 | HP160014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 종 반응성 | Human, Mouse, Rat | ||||||||
| 응용 분야 | ELISA, IHC, WB | ||||||||
| 숙주 종 | Rabbit | ||||||||
| 클론성 | Polyclonal | ||||||||
| 이소타입 | IgG | ||||||||
| 면역원 | E. coli - derived recombinant Human NDEL1 (Asp8-Lys193). | ||||||||
| 타겟 | Protein Nudel, EOPA, Nuclear distribution protein nudE-like 1, NUDEL, MITAP1, NDEL1, Mitosin-associated protein 1 | ||||||||
| 정제 | Purified by antigen affinity column. | ||||||||
| 등록번호 | Q9GZM8 | ||||||||
| 형태 | Liquid | ||||||||
| 저장 완충액 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 배경 | Nuclear distribution protein nudE-like 1 (NDEL1) is a ~38 kDa protein. Required for organization of the cellular microtubule array and microtubule anchoring at the centrosome. May regulate microtubule organization at least in part by targeting the microtubule severing protein KATNA1 to the centrosome. Also positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus ends. Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the centripetal motion of secretory vesicles and the coupling of the nucleus and centrosome. 1. Zhang, Y. et al. (2022) Structure (London, England : 1993) 30, 386-395.e5. PMID: 34793709 | ||||||||
| 참고사항 | For research use only. |
Western blot analysis was performed using anti-NDEL1 polyclonal antibody at 1μg/ml on various samples.
Lane 1: Mouse brain lysate
Lane 2: Rat brain lysate
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