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| 카탈로그 번호 | HA033013 | ||||
|---|---|---|---|---|---|
| 종 반응성 | Human | ||||
| 응용 분야 | ELISA | ||||
| 숙주 종 | Mouse | ||||
| 클론성 | Monoclonal | ||||
| 이소타입 | IgG2a, kappa | ||||
| 클론 ID | SAA1925 | ||||
| 타겟 | NME7, Nucleoside diphosphate kinase 7, NDP kinase 7, NDK 7, nm23-H7 | ||||
| 내독소 수준 | Please contact with the lab for this information. | ||||
| 순도 | >95% as determined by SDS-PAGE. | ||||
| 정제 | Protein A/G purified from cell culture supernatant. | ||||
| 등록번호 | Q9Y5B8 | ||||
| RRID | Anti-Human NME7 Antibody (SAA1925) (abinScience Cat# HA033013, RRID:AB_3727689) |
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| 형태 | Liquid | ||||
| 저장 완충액 | 0.01M PBS pH 7.4 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. | ||||
| 배경 | Nucleoside diphosphate kinase 7 (NME7) is a ~42 kDa protein. Possesses an intrinsic kinase activity. Phosphorylates GSK3B at 'Ser-9', leading to the activation of Wnt/beta-catenin signaling. Additionally, exhibits a 3'-5'-DNA exonuclease activity that removes single nucleotides from the 3' terminus of single-stranded DNA substrates and digests overhanging mismatched 3' termini from double-stranded DNA substrates, possibly participating in DNA nucleolytic processing. In vitro, does not seem to have nucleoside diphosphate kinase activity. Functional component of the gamma-tubulin ring complex, implicated in the regulation of its microtubule-nucleating activity in centrosomes, in a kinase activity-dependent manner. 1. Liu, P. et al. (2014) Molecular biology of the cell 25, 2017-25. PMID: 24807905 2. Ren, X. et al. (2022) Cancer research 82, 60-74. PMID: 34764205 3. Yoon, JH. et al. (2005) Biochemistry 44, 15774-86. PMID: 16313181 4. Ji, M. et al. (2025) Life science alliance 8. PMID: 39824631 5. Gui, M. et al. (2022) Proceedings of the National Academy of Sciences of the United States of America 119, e2207605119. PMID: 36191189 | ||||
| 참고사항 | For research use only. |
SDS-PAGE for Anti-Human NME7 Antibody (SAA1925)
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