Anti-Human NMT1 Polyclonal Antibody (HB608014)

Name: Anti-Human NMT1 Polyclonal Antibody
Brand: abinScience
SKU: HB608014
Price: 168 USD
Availability: InStock

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개요
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개요

카탈로그 번호

HB608014

설명

Anti-Human NMT1 Polyclonal Antibody (HB608014) is a rabbit polyclonal antibody detecting NMT1 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

종 반응성

Human, Mouse, Rat

응용 분야

ELISA, IHC, WB

숙주 종

Rabbit

클론성

Polyclonal

이소타입

IgG

면역원

E. coli - derived recombinant Human NMT1 (Thr108-Gln496).

타겟

Myristoyl-CoA:protein N-myristoyltransferase 1, Type I N-myristoyltransferase, NMT 1, Peptide N-myristoyltransferase 1, NMT1, Glycylpeptide N-tetradecanoyltransferase 1, NMT

정제

Purified by antigen affinity column.

등록번호

P30419

형태

Liquid

저장 완충액

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

제품 사용 정보

응용 분야	희석
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

안정성 및 저장

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

배경

Glycylpeptide N-tetradecanoyltransferase 1 (NMT1) is a ~56 kDa protein. Adds a myristoyl group to the N-terminal glycine residue of certain cellular and viral proteins. Also able to mediate N-terminal lysine myristoylation of proteins: catalyzes myristoylation of ARF6 on both 'Gly-2' and 'Lys-3'. Lysine myristoylation is required to maintain ARF6 on membranes during the GTPase cycle.

1. Montgomery, C. et al. (2012) The Journal of biological chemistry 287, 33227-36. PMID: 22865860

2. Thinon, E. et al. (2014) Nature communications 5, 4919. PMID: 25255805

3. Chen, YC. et al. (2020) Scientific reports 10, 11952. PMID: 32686708

4. Sun, Y. et al. (2022) Cancer letters 529, 126-138. PMID: 34999170

5. Glover, CJ. et al. (1997) The Journal of biological chemistry 272, 28680-9. PMID: 9353336

6. Giang, DK. et al. (1998) The Journal of biological chemistry 273, 6595-8. PMID: 9506952

7. Kosciuk, T. et al. (2020) Nature communications 11, 1067. PMID: 32103017

8. Dian, C. et al. (2020) Nature communications 11, 1132. PMID: 32111831

참고사항

For research use only.

이미지

참고 문헌

데이터시트

Anti-Human NMT1 Polyclonal Antibody.pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

재조합 단백질

항체

어세이 키트

Anti-Human NMT1 Polyclonal Antibody (HB608014)

개요

이미지

참고 문헌

데이터시트

SDS