中文
English
한국어
日本語
Español
Français
Русский
| 카탈로그 번호 | HB010013 | ||||
|---|---|---|---|---|---|
| 설명 |
Anti-Human NPR1/NPR-A Recombinant Antibody (SAA1818) (HB010013) is a human monoclonal antibody detecting NPR1/NPR-A in ELISA. Suitable for Human.
Highlights
|
||||
| 종 반응성 | Human | ||||
| 응용 분야 | ELISA | ||||
| 숙주 종 | Human | ||||
| 클론성 | Monoclonal | ||||
| 이소타입 | IgG4, kappa | ||||
| 클론 ID | SAA1818 | ||||
| 타겟 | ANP-A, Atrial natriuretic peptide receptor type A, Guanylate cyclase A, NPR1, NPR-A, ANPRA, GC-A, ANPR-A, Atrial natriuretic peptide receptor 1 | ||||
| 내독소 수준 | < 10 EU/mg as determined by LAL method. | ||||
| 순도 | >95% as determined by SDS-PAGE. | ||||
| 정제 | Protein A/G purified from cell culture supernatant. | ||||
| 등록번호 | P16066 | ||||
| RRID | Anti-Human NPR1/NPR-A Antibody (SAA1818) (abinScience Cat# HB010013, RRID:AB_3727580) |
||||
| 형태 | Liquid | ||||
| 저장 완충액 | 0.01M PBS pH 7.4. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
||||
| 제품 사용 정보 |
| ||||
| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. | ||||
| 배경 | Atrial natriuretic peptide receptor 1 (NPR1/NPR-A) is a ~118 kDa protein. Receptor for the atrial natriuretic peptide NPPA/ANP and the brain natriuretic peptide NPPB/BNP which are potent vasoactive hormones playing a key role in cardiovascular homeostasis. Plays an essential role in the regulation of endothelial cell senescence and vascular aging. Upon activation by ANP or BNP, stimulates the production of cyclic guanosine monophosphate (cGMP) that promotes vascular tone and volume homeostasis by activation of protein kinase cGMP-dependent 1/PRKG1 and subsequently PRKAA1, thereby controlling blood pressure and maintaining cardiovascular homeostasis. 1. Liu, S. et al. (2025) Nature structural & molecular biology 32, 469-478. PMID: 39543315 2. Long, C. et al. (2022) Aging cell 21, e13699. PMID: 36016499 | ||||
| 참고사항 | For research use only. | ||||
| Isotype Control | Human IgG4 (S228P) Recombinant Isotype Control Antibody (13R4) (HP298207) |
SDS-PAGE for Anti-Human NPR1/NPR-A Antibody (SAA1818).
문의하기
+86-027-65523339
중국 우한시 심둔사로 666번지 C동, 우한, 430206
