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| 카탈로그 번호 | HY360013 | ||||
|---|---|---|---|---|---|
| 종 반응성 | Human | ||||
| 응용 분야 | Blocking, ELISA | ||||
| 숙주 종 | Mouse | ||||
| 클론성 | Monoclonal | ||||
| 이소타입 | IgG2a, kappa | ||||
| 클론 ID | KTM219 | ||||
| 타겟 | Gamma-carboxyglutamic acid-containing protein, BGLAP, BGP, Bone Gla protein, Osteocalcin | ||||
| 내독소 수준 | Please contact with the lab for this information. | ||||
| 순도 | >95% as determined by SDS-PAGE. | ||||
| 정제 | Protein A/G purified from cell culture supernatant. | ||||
| 등록번호 | P02818 | ||||
| RRID | Anti-Human Osteocalcin/BGP/OC Antibody (KTM219) (abinScience Cat# HY360013, RRID:AB_3727191) |
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| 형태 | Liquid | ||||
| 저장 완충액 | 0.01M PBS pH 7.4 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. | ||||
| 배경 | Osteocalcin (BGLAP) is a ~10 kDa protein. The carboxylated form is one of the main organic components of the bone matrix, which constitutes 1-2% of the total bone protein. Acts as a negative regulator of bone formation and is required to limit bone formation without impairing bone resorption or mineralization. Binds strongly to apatite and calcium upon gamma-carboxylation; this modification is essential for bone metabolism. 1. Celeste, AJ. et al. (1986) The EMBO journal 5, 1885-90. PMID: 3019668 2. Poser, JW. et al. (1980) The Journal of biological chemistry 255, 8685-91. PMID: 6967872 3. Wang, R. et al. (2025) Nature 639, 808-815. PMID: 39880952 | ||||
| 참고사항 | For research use only. | ||||
| Isotype Control | Mouse IgG2a (Fc Silence) Recombinant Isotype Control (MOPC 173) (MF533023) |
SDS-PAGE for Anti-Human Osteocalcin/BGP/OC Antibody (KTM219).
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