

| 카탈로그 번호 | HT117014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 설명 |
Anti-Human P2RX6 Polyclonal Antibody (HT117014) is a rabbit polyclonal antibody detecting P2RX6 in ELISA, IHC, WB. Suitable for Human.
Highlights
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| 종 반응성 | Human | ||||||||
| 응용 분야 | ELISA, IHC, WB | ||||||||
| 숙주 종 | Rabbit | ||||||||
| 클론성 | Polyclonal | ||||||||
| 이소타입 | IgG | ||||||||
| 면역원 | E. coli - derived recombinant Human P2RX6 (Lys61-Gly333). | ||||||||
| 타겟 | Purinergic receptor, P2XM, Purinergic receptor P2X-like 1, P2RXL1, P2X purinoceptor 6, P2X6, ATP receptor, P2RX6 | ||||||||
| 정제 | Purified by antigen affinity column. | ||||||||
| 등록번호 | O15547 | ||||||||
| 형태 | Liquid | ||||||||
| 저장 완충액 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 배경 | P2X purinoceptor 6 (P2RX6) is a ~48 kDa protein. May act as a modulatory subunit rather than a functional channel. Unlike other P2XRs members, P2RX6 does not seem to form functional homotrimers. P2RX6 requires the presence of P2RX4 or P2RX2 to shuttle it to the plasma membrane where it may form functional heterotrimeric receptors at the plasma membrane. P2RX6 can be translocated to the nucleus and functions as a nuclear regulator of post-transcriptional modifications in neurons. 1. Hausmann, R. et al. (2012) The Journal of biological chemistry 287, 13930-43. PMID: 22378790 | ||||||||
| 참고사항 | For research use only. |
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