Anti-Human PANX1 Polyclonal Antibody (HP450014)

Name: Anti-Human PANX1 Polyclonal Antibody
Brand: abinScience
SKU: HP450014
Price: 168 USD
Availability: InStock

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개요
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참고 문헌
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SDS

개요

카탈로그 번호

HP450014

설명

Anti-Human PANX1 Polyclonal Antibody (HP450014) is a rabbit polyclonal antibody detecting PANX1 in ELISA, IHC, WB. Suitable for Human.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

종 반응성

Human

응용 분야

ELISA, IHC, WB

숙주 종

Rabbit

클론성

Polyclonal

이소타입

IgG

면역원

E. coli - derived recombinant Human PANX1 (Ser236-Gln274).

타겟

MRS1, Pannexin-1, PANX1

정제

Purified by antigen affinity column.

등록번호

Q96RD7

형태

Liquid

저장 완충액

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

제품 사용 정보

응용 분야	희석
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

안정성 및 저장

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

배경

Pannexin-1 (PANX1) is a ~48 kDa protein. Ion channel involved in a variety of physiological functions such as blood pressure regulation, apoptotic cell clearance and oogenesis. Forms anion-selective channels with relatively low conductance and an order of permeabilities: nitrate>iodide>chlroride>>aspartate=glutamate=gluconate. Can release ATP upon activation through phosphorylation or cleavage at C-terminus. May play a role as a Ca(2+)-leak channel to regulate ER Ca(2+) homeostasis.

1. Bao, L. et al. (2004) FEBS letters 572, 65-8. PMID: 15304325

2. Vanden Abeele, F. et al. (2006) The Journal of cell biology 174, 535-46. PMID: 16908669

3. Bunse, S. et al. (2010) The Journal of biological chemistry 285, 38444-52. PMID: 20829356

4. Chekeni, FB. et al. (2010) Nature 467, 863-7. PMID: 20944749

5. Sang, Q. et al. (2019) Science translational medicine 11. PMID: 30918116

6. Medina, CB. et al. (2020) Nature 580, 130-135. PMID: 32238926

참고사항

For research use only.

이미지

참고 문헌

데이터시트

Anti-Human PANX1 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

재조합 단백질

항체

어세이 키트

Anti-Human PANX1 Polyclonal Antibody (HP450014)

개요

이미지

참고 문헌

데이터시트

SDS