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Anti-Human PCBP2 Polyclonal Antibody (HS896014)

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개요
카탈로그 번호HS896014
설명
Anti-Human PCBP2 Polyclonal Antibody (HS896014) is a rabbit polyclonal antibody detecting PCBP2 in ELISA, IHC, WB. Suitable for Human, Mouse.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
  • ●Multi-Species — Cross-reactive for translational research.
종 반응성Human, Mouse
응용 분야ELISA, IHC, WB
숙주 종Rabbit
클론성Polyclonal
이소타입IgG
면역원 E. coli - derived recombinant Human PCBP2 (Asn11-Ser173).
타겟 Heterogeneous nuclear ribonucleoprotein E2, Alpha-CP2, hnRNP E2, Poly(rC)-binding protein 2, PCBP2
정제 Purified by antigen affinity column.
등록번호 Q15366
형태 Liquid
저장 완충액 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

제품 사용 정보
응용 분야 희석
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
안정성 및 저장 Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
배경

Poly(rC)-binding protein 2 (PCBP2) is a ~38 kDa protein. Single-stranded nucleic acid binding protein that binds preferentially to oligo dC. Major cellular poly(rC)-binding protein. Also binds poly(rU). Acts as a negative regulator of antiviral signaling. Negatively regulates cellular antiviral responses mediated by MAVS signaling.

1. Walter, BL. et al. (2002) Journal of virology 76, 12008-22. PMID: 12414943
2. Leffers, H. et al. (1995) European journal of biochemistry 230, 447-53. PMID: 7607214
3. You, F. et al. (2009) Nature immunology 10, 1300-8. PMID: 19881509
4. Gu, H. et al. (2022) Nature communications 13, 1564. PMID: 35322803
참고사항 For research use only.
이미지
참고 문헌
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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