Anti-Human PEX14 Polyclonal Antibody (HF863014)

Name: Anti-Human PEX14 Polyclonal Antibody
Brand: abinScience
SKU: HF863014
Price: 168 USD
Availability: InStock

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개요
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개요

카탈로그 번호

HF863014

설명

Anti-Human PEX14 Polyclonal Antibody (HF863014) is a rabbit polyclonal antibody detecting PEX14 in ELISA, IHC, WB. Suitable for Human, Mouse, and Rat.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

종 반응성

Human, Mouse, Rat

응용 분야

ELISA, IHC, WB

숙주 종

Rabbit

클론성

Polyclonal

이소타입

IgG

면역원

E. coli - derived recombinant Human PEX14 (Arg25-Glu76).

타겟

Peroxisomal membrane protein PEX14, PTS1 receptor-docking protein, Peroxin-14, PEX14, Peroxisomal membrane anchor protein PEX14

정제

Purified by antigen affinity column.

등록번호

O75381

형태

Liquid

저장 완충액

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

제품 사용 정보

응용 분야	희석
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

안정성 및 저장

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

배경

Peroxisomal membrane protein PEX14 is a ~41 kDa protein. Component of the PEX13-PEX14 docking complex, a translocon channel that specifically mediates the import of peroxisomal cargo proteins bound to PEX5 receptor. The PEX13-PEX14 docking complex forms a large import pore which can be opened to a diameter of about 9 nm. Mechanistically, PEX5 receptor along with cargo proteins associates with the PEX14 subunit of the PEX13-PEX14 docking complex in the cytosol, leading to the insertion of the receptor into the organelle membrane with the concomitant translocation of the cargo into the peroxisome matrix. Plays a key role for peroxisome movement through a direct interaction with tubulin.

1. Neuhaus, A. et al. (2014) The Journal of biological chemistry 289, 437-48. PMID: 24235149

2. Dias, AF. et al. (2017) The Journal of biological chemistry 292, 15287-15300. PMID: 28765278

3. Fransen, M. et al. (1998) Proceedings of the National Academy of Sciences of the United States of America 95, 8087-92. PMID: 9653144

4. Bharti, P. et al. (2011) Journal of cell science 124, 1759-68. PMID: 21525035

참고사항

For research use only.

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참고 문헌

데이터시트

Anti-Human PEX14 Polyclonal Antibody.pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

재조합 단백질

항체

어세이 키트

Anti-Human PEX14 Polyclonal Antibody (HF863014)

개요

이미지

참고 문헌

데이터시트

SDS