Anti-Human PLA2G10 Polyclonal Antibody (HT102014)

Name: Anti-Human PLA2G10 Polyclonal Antibody
Brand: abinScience
SKU: HT102014
Price: 168 USD
Availability: InStock

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개요
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참고 문헌
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SDS

개요

카탈로그 번호

HT102014

설명

Anti-Human PLA2G10 Polyclonal Antibody (HT102014) is a rabbit polyclonal antibody detecting PLA2G10. Suitable for Human.

종 반응성

Human

응용 분야

ELISA, IHC, WB

숙주 종

Rabbit

클론성

Polyclonal

이소타입

IgG

면역원

E. coli - derived recombinant Human PLA2G10 (Glu32-Asp165).

타겟

EC:3.1.1.4, GX sPLA2, Group 10 secretory phospholipase A2, Group X secretory phospholipase A2, PLA2G10, Phosphatidylcholine 2-acylhydrolase 10, sPLA2-X

내독소 수준

Please contact with the lab for this information.

정제

Purified by antigen affinity column.

등록번호

O15496

형태

Liquid

저장 완충액

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

제품 사용 정보

응용 분야	희석
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

배경

Group 10 secretory phospholipase A2 (PLA2G10) is a ~18 kDa protein. Secretory calcium-dependent phospholipase A2 that primarily targets extracellular phospholipids. Hydrolyzes the ester bond of the fatty acyl group attached at sn-2 position of phospholipids with preference for phosphatidylcholines and phosphatidylglycerols over phosphatidylethanolamines. Preferentially releases sn-2 omega-6 and omega-3 polyunsaturated fatty acyl (PUFA) chains over saturated fatty acyls. Contributes to phospholipid remodeling of very low-density lipoprotein (VLDL), low-density lipoprotein (LDL) and high-density lipoprotein (HDL) particles. Hydrolyzes LDL phospholipids releasing unsaturated fatty acids that regulate macrophage differentiation toward foam cells.

1. Hanasaki, K. et al. (2002) The Journal of biological chemistry 277, 29116-24. PMID: 12021277

2. Cupillard, L. et al. (1997) The Journal of biological chemistry 272, 15745-52. PMID: 9188469

3. Singer, AG. et al. (2002) The Journal of biological chemistry 277, 48535-49. PMID: 12359733

4. Gora, S. et al. (2006) Biochimica et biophysica acta 1761, 1093-9. PMID: 16962371

5. Koduri, RS. et al. (2002) The Journal of biological chemistry 277, 5849-57. PMID: 11694541

6. Mitsuishi, M. et al. (2006) The Biochemical journal 393, 97-106. PMID: 16146426

참고사항

For research use only

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참고 문헌

데이터시트

Anti-Human PLA2G10 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

재조합 단백질

항체

어세이 키트

Anti-Human PLA2G10 Polyclonal Antibody (HT102014)

개요

이미지

참고 문헌

데이터시트

SDS