Anti-Human PLCG1 Polyclonal Antibody (HB687014)

Name: Anti-Human PLCG1 Polyclonal Antibody
Brand: abinScience
SKU: HB687014
Price: 168 USD
Availability: InStock

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사양:

50ug
100ug

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개요
이미지
참고 문헌
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SDS

개요

카탈로그 번호

HB687014

설명

Anti-Human PLCG1 Polyclonal Antibody (HB687014) is a rabbit polyclonal antibody detecting PLCG1. Suitable for Mouse, Human, and Rat.

Highlights

●Multi-Species — Cross-reactive for translational research.

종 반응성

Human, Mouse, Rat

응용 분야

ELISA, IHC, WB

숙주 종

Rabbit

클론성

Polyclonal

이소타입

IgG

면역원

E. coli - derived recombinant Human PLCG1 (His545-Ile764).

타겟

1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1, EC:3.1.4.11, PLC-148, PLC-II, PLC-gamma-1, PLC1, PLCG1, Phosphoinositide phospholipase C-gamma-1, Phospholipase C-II, Phospholipase C-gamma-1

내독소 수준

Please contact with the lab for this information.

정제

Purified by antigen affinity column.

등록번호

P19174

형태

Liquid

저장 완충액

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

제품 사용 정보

응용 분야	희석
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

배경

1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 (PLCG1) is a ~148 kDa protein. Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. Becomes activated in response to ligand-mediated activation of receptor-type tyrosine kinases, such as PDGFRA, PDGFRB, EGFR, FGFR1, FGFR2, FGFR3 and FGFR4. Plays a role in actin reorganization and cell migration. Guanine nucleotide exchange factor that binds the GTPase DNM1 and catalyzes the dissociation of GDP, allowing a GTP molecule to bind in its place, therefore enhancing DNM1-dependent endocytosis.

1. Wang, Y. et al. (2007) American journal of physiology. Cell physiology 292, C1775-86. PMID: 17229814

참고사항

For research use only.

이미지

Western blot

Western blot analysis was performed using anti-PLCG1 polyclonal antibody at 1ug/mL on various samples.
Lane 1: A431 cell lysate
Lane 2: 293T cell lysate
Lane 3: Raji cell lysate

참고 문헌

데이터시트

Anti-Human PLCG1 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

재조합 단백질

항체

어세이 키트

Anti-Human PLCG1 Polyclonal Antibody (HB687014)

개요

이미지

참고 문헌

데이터시트

SDS