Anti-Human PNPT1 Polyclonal Antibody (HC241014)

Name: Anti-Human PNPT1 Polyclonal Antibody
Brand: abinScience
SKU: HC241014
Price: 168 USD
Availability: InStock

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사양:

50ug
100ug

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개요
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참고 문헌
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SDS

개요

카탈로그 번호

HC241014

설명

Anti-Human PNPT1 Polyclonal Antibody (HC241014) is a rabbit polyclonal antibody detecting PNPT1. Suitable for Mouse and Human.

Highlights

●Multi-Species — Cross-reactive for translational research.

종 반응성

Human, Mouse

응용 분야

ELISA, IHC, WB

숙주 종

Rabbit

클론성

Polyclonal

이소타입

IgG

면역원

E. coli - derived recombinant Human PNPT1 (Gly43-Lys595).

타겟

3'-5' RNA exonuclease OLD35, EC:2.7.7.8, PNPASE, PNPT1, PNPase 1, PNPase old-35, Polynucleotide phosphorylase 1, Polynucleotide phosphorylase-like protein, Polyribonucleotide nucleotidyltransferase 1, mitochondrial

내독소 수준

Please contact with the lab for this information.

정제

Purified by antigen affinity column.

등록번호

Q8TCS8

형태

Liquid

저장 완충액

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

제품 사용 정보

응용 분야	희석
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

배경

Polyribonucleotide nucleotidyltransferase 1, mitochondrial (PNPT1) is a ~85 kDa protein. RNA-binding protein implicated in numerous RNA metabolic processes. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'-to-5' direction. Mitochondrial intermembrane factor with RNA-processing exoribonulease activity. Component of the mitochondrial degradosome (mtEXO) complex, that degrades 3' overhang double-stranded RNA with a 3'-to-5' directionality in an ATP-dependent manner. Involved in the degradation of non-coding mitochondrial transcripts (MT-ncRNA) and tRNA-like molecules.

1. Pietras, Z. et al. (2018) Nature communications 9, 2558. PMID: 29967381

2. Kim, S. et al. (2024) Molecular cell 84, 2935-2948.e7. PMID: 39019044

참고사항

For research use only

이미지

참고 문헌

데이터시트

Anti-Human PNPT1 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

재조합 단백질

항체

어세이 키트

Anti-Human PNPT1 Polyclonal Antibody (HC241014)

개요

이미지

참고 문헌

데이터시트

SDS