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| 카탈로그 번호 | HA239014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 설명 |
Anti-Human PPARGC1B Polyclonal Antibody (HA239014) is a rabbit polyclonal antibody detecting PPARGC1B in ELISA, IHC, WB. Suitable for Human.
Highlights
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| 종 반응성 | Human | ||||||||
| 응용 분야 | ELISA, IHC, WB | ||||||||
| 숙주 종 | Rabbit | ||||||||
| 클론성 | Polyclonal | ||||||||
| 이소타입 | IgG | ||||||||
| 면역원 | E. coli - derived recombinant Human PPARGC1B (Ser886-His1023). | ||||||||
| 타겟 | Peroxisome proliferator-activated receptor gamma coactivator 1-beta, PGC-1-beta, PPAR-gamma coactivator 1-beta, PPARGC-1-beta, PGC-1-related estrogen receptor alpha coactivator, PPARGC1B, PERC, PGC1, PGC1B, PPARGC1 | ||||||||
| 정제 | Purified by antigen affinity column. | ||||||||
| 등록번호 | Q86YN6 | ||||||||
| 형태 | Liquid | ||||||||
| 저장 완충액 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 배경 | Peroxisome proliferator-activated receptor gamma coactivator 1-beta (PPARGC1B) is a ~113 kDa protein. Plays a role of stimulator of transcription factors and nuclear receptors activities. Activates transcriptional activity of estrogen receptor alpha, nuclear respiratory factor 1 (NRF1) and glucocorticoid receptor in the presence of glucocorticoids. May play a role in constitutive non-adrenergic-mediated mitochondrial biogenesis as suggested by increased basal oxygen consumption and mitochondrial number when overexpressed. May be involved in fat oxidation and non-oxidative glucose metabolism and in the regulation of energy expenditure. Induces the expression of PERM1 in the skeletal muscle in an ESRRA-dependent manner. | ||||||||
| 참고사항 | For research use only. |
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