Anti-Human PPP2R2A Polyclonal Antibody (HX167014)

Name: Anti-Human PPP2R2A Polyclonal Antibody
Brand: abinScience
SKU: HX167014
Price: 168 USD
Availability: InStock

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100ug

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개요
이미지
참고 문헌
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SDS

개요

카탈로그 번호

HX167014

설명

Anti-Human PPP2R2A Polyclonal Antibody (HX167014) is a rabbit polyclonal antibody detecting PPP2R2A in ELISA, IHC, WB. Suitable for Human.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

종 반응성

Human, Mouse, Rat

응용 분야

ELISA, IHC, WB

숙주 종

Rabbit

클론성

Polyclonal

이소타입

IgG

면역원

E. coli - derived recombinant Human PPP2R2A (Met1-Asn447).

타겟

PP2A subunit B isoform R2-alpha, Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform, PP2A subunit B isoform PR55-alpha, PPP2R2A, PP2A subunit B isoform alpha, PP2A subunit B isoform B55-alpha

정제

Purified by antigen affinity column.

등록번호

P63151

형태

Liquid

저장 완충액

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

제품 사용 정보

응용 분야	희석
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

안정성 및 저장

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

배경

Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform (PPP2R2A) is a ~51 kDa protein. Substrate-recognition subunit of protein phosphatase 2A (PP2A) that plays a key role in cell cycle by controlling mitosis entry and exit. Involved in chromosome clustering during late mitosis by mediating dephosphorylation of MKI67. Essential for serine/threonine-protein phosphatase 2A-mediated dephosphorylation of WEE1, preventing its ubiquitin-mediated proteolysis, increasing WEE1 protein levels, and promoting the G2/M checkpoint.

1. Mayer, RE. et al. (1991) Biochemistry 30, 3589-97. PMID: 1849734

2. Li, F. et al. (2020) Molecular cell 80, 410-422.e6. PMID: 33108758

참고사항

For research use only.

이미지

참고 문헌

데이터시트

Anti-Human PPP2R2A Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

재조합 단백질

항체

어세이 키트

Anti-Human PPP2R2A Polyclonal Antibody (HX167014)

개요

이미지

참고 문헌

데이터시트

SDS