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| 카탈로그 번호 | HB999013 | ||||
|---|---|---|---|---|---|
| 종 반응성 | Human | ||||
| 응용 분야 | ELISA | ||||
| 숙주 종 | Mouse | ||||
| 클론성 | Monoclonal | ||||
| 이소타입 | IgG2a, kappa | ||||
| 클론 ID | SAA1620 | ||||
| 타겟 | 24 kDa protein, Lysophosphatidylcholine acyltransferase 5, Acidic calcium-independent phospholipase A2, KIAA0106, LPCAT-5, 1-Cys PRX, Antioxidant protein 2, LPC acyltransferase 5, aiPLA2, Non-selenium glutathione peroxidase, Lyso-PC acyltransferase 5, PRDX6, AOP2, Glutathione-dependent peroxiredoxin, Peroxiredoxin-6, NSGPx, Red blood cells page spot 12, 1-Cys peroxiredoxin, Liver 2D page spot 40 | ||||
| 내독소 수준 | Please contact with the lab for this information. | ||||
| 순도 | >95% as determined by SDS-PAGE. | ||||
| 정제 | Protein A/G purified from cell culture supernatant. | ||||
| 등록번호 | P30041 | ||||
| RRID | Anti-Human PRDX6 Antibody (SAA1620) (abinScience Cat# HB999013, RRID:AB_3727381) |
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| 형태 | Liquid | ||||
| 저장 완충액 | 0.01M PBS pH 7.4 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. | ||||
| 배경 | Peroxiredoxin-6 (PRDX6) is a ~25 kDa protein. Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Can reduce H(2)O(2) and short chain organic, fatty acid, and phospholipid hydroperoxides. Also has phospholipase activity, can therefore either reduce the oxidized sn-2 fatty acyl group of phospholipids (peroxidase activity) or hydrolyze the sn-2 ester bond of phospholipids (phospholipase activity). These activities are dependent on binding to phospholipids at acidic pH and to oxidized phospholipds at cytosolic pH. Plays a role in cell protection against oxidative stress by detoxifying peroxides and in phospholipid homeostasis. 1. Chen, JW. et al. (2000) The Journal of biological chemistry 275, 28421-7. PMID: 10893423 2. Kang, SW. et al. (1998) The Journal of biological chemistry 273, 6303-11. PMID: 9497358 3. Fisher, AB. et al. (2016) Journal of lipid research 57, 587-96. PMID: 26830860 | ||||
| 참고사항 | For research use only. |
SDS-PAGE for Anti-Human PRDX6 Antibody (SAA1620)
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