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Anti-Human PRDX6 Polyclonal Antibody (HB999014)

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개요
카탈로그 번호HB999014
설명
Anti-Human PRDX6 Polyclonal Antibody (HB999014) is a rabbit polyclonal antibody detecting PRDX6 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat, Bovine, and Chicken.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
  • ●Multi-Species — Cross-reactive for translational research.
종 반응성Human, Rat
응용 분야ELISA, IHC, WB
숙주 종Rabbit
클론성Polyclonal
이소타입IgG
면역원 E. coli - derived recombinant Human PRDX6 (Met1-Pro224).
타겟 24 kDa protein, Lysophosphatidylcholine acyltransferase 5, Acidic calcium-independent phospholipase A2, KIAA0106, LPCAT-5, 1-Cys PRX, Antioxidant protein 2, LPC acyltransferase 5, aiPLA2, Non-selenium glutathione peroxidase, Lyso-PC acyltransferase 5, PRDX6, AOP2, Glutathione-dependent peroxiredoxin, Peroxiredoxin-6, NSGPx, Red blood cells page spot 12, 1-Cys peroxiredoxin, Liver 2D page spot 40
정제 Purified by antigen affinity column.
등록번호 P30041
형태 Liquid
저장 완충액 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

제품 사용 정보
응용 분야 희석
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
안정성 및 저장 Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
배경

Peroxiredoxin-6 (PRDX6) is a ~25 kDa protein. Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Can reduce H(2)O(2) and short chain organic, fatty acid, and phospholipid hydroperoxides. Also has phospholipase activity, can therefore either reduce the oxidized sn-2 fatty acyl group of phospholipids (peroxidase activity) or hydrolyze the sn-2 ester bond of phospholipids (phospholipase activity). These activities are dependent on binding to phospholipids at acidic pH and to oxidized phospholipds at cytosolic pH. Plays a role in cell protection against oxidative stress by detoxifying peroxides and in phospholipid homeostasis.

1. Chen, JW. et al. (2000) The Journal of biological chemistry 275, 28421-7. PMID: 10893423
2. Kang, SW. et al. (1998) The Journal of biological chemistry 273, 6303-11. PMID: 9497358
3. Fisher, AB. et al. (2016) Journal of lipid research 57, 587-96. PMID: 26830860
참고사항 For research use only.
이미지
참고 문헌
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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