

| 카탈로그 번호 | HD153014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 설명 |
Anti-Human PRPF6 Polyclonal Antibody (HD153014) is a rabbit polyclonal antibody detecting PRPF6. Suitable for Rat, Human, and Mouse.
Highlights
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| 종 반응성 | Human, Mouse, Rat | ||||||||
| 응용 분야 | ELISA, IHC, WB | ||||||||
| 숙주 종 | Rabbit | ||||||||
| 클론성 | Polyclonal | ||||||||
| 이소타입 | IgG | ||||||||
| 면역원 | E. coli - derived recombinant Human PRPF6 (Lys606-Phe941). | ||||||||
| 타겟 | ANT-1, Androgen receptor N-terminal domain-transactivating protein 1, C20orf14, PRP6 homolog, PRPF6, Pre-mRNA-processing factor 6, U5 snRNP-associated 102 kDa protein, U5-102 kDa protein | ||||||||
| 내독소 수준 | Please contact with the lab for this information. | ||||||||
| 정제 | Purified by antigen affinity column. | ||||||||
| 등록번호 | O94906 | ||||||||
| 형태 | Liquid | ||||||||
| 저장 완충액 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 배경 | Pre-mRNA-processing factor 6 (PRPF6) is a ~106 kDa protein. Involved in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex, one of the building blocks of the spliceosome. Enhances dihydrotestosterone-induced transactivation activity of AR, as well as dexamethasone-induced transactivation activity of NR3C1, but does not affect estrogen-induced transactivation. 1. Schneider, M. et al. (2010) Nature structural & molecular biology 17, 216-21. PMID: 20118938 2. Tanackovic, G. et al. (2011) American journal of human genetics 88, 643-9. PMID: 21549338 3. Bertram, K. et al. (2017) Cell 170, 701-713.e11. PMID: 28781166 | ||||||||
| 참고사항 | For research use only |

Western blot analysis was performed using anti-PRPF6 polyclonal antibody at 1ug/mL on various samples.
Lane 1: K562 cell lysate
Lane 2: HL-60 cell lysate


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