Anti-Human PCPTP1 Polyclonal Antibody (HA962014)

Name: Anti-Human PCPTP1 Polyclonal Antibody
Brand: abinScience
SKU: HA962014
Price: 168 USD
Availability: InStock

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개요
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SDS

개요

카탈로그 번호

HA962014

설명

Anti-Human PTPRQ Polyclonal Antibody (HA962014) is a rabbit polyclonal antibody detecting PTPRQ in ELISA, IHC, WB. Suitable for Human.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

종 반응성

Human, Mouse, Rat

응용 분야

ELISA, IHC, WB

숙주 종

Rabbit

클론성

Polyclonal

이소타입

IgG

면역원

E. coli - derived recombinant Human PTPRQ (Arg1929-Met2299).

타겟

Phosphatidylinositol phosphatase PTPRQ, R-PTP-Q, PTP-RQ, PTPRQ, Receptor-type tyrosine-protein phosphatase Q

내독소 수준

Please contact with the lab for this information.

순도

>95% as determined by SDS-PAGE.

정제

Purified by antigen affinity column.

등록번호

Q9UMZ3

형태

Liquid

저장 완충액

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

제품 사용 정보

응용 분야	희석
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

안정성 및 저장

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

배경

Phosphatidylinositol phosphatase PTPRQ is a ~260 kDa protein. Dephosphorylates phosphatidylinositol phosphates, such as phosphatidylinositol 3,4,5-trisphosphate (PIP3) and phosphatidylinositol 3,5-diphosphates, with preference for PIP3. Phosphate can be hydrolyzed from the D3 and D5 positions in the inositol ring. Has low tyrosine-protein phosphatase activity in vitro; however, the relevance of such activity in vivo is unclear. Plays an important role in adipogenesis of mesenchymal stem cells (MSCs). Regulates the phosphorylation state of AKT1 by regulating the levels of PIP3 in MSCs and preadipocyte cells.

1. Yu, KR. et al. (2013) Acta crystallographica. Section D, Biological crystallography 69, 1522-9. PMID: 23897475

2. Jung, H. et al. (2009) Biochemical and biophysical research communications 383, 252-7. PMID: 19351528

3. Shahin, H. et al. (2010) Journal of medical genetics 47, 643-5. PMID: 20472657

4. Eisenberger, T. et al. (2018) Genetics in medicine : official journal of the American College of Medical Genetics 20, 614-621. PMID: 29309402

참고사항

For research use only.

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참고 문헌

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Anti-Human PCPTP1 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

재조합 단백질

항체

어세이 키트

Anti-Human PCPTP1 Polyclonal Antibody (HA962014)

개요

이미지

참고 문헌

데이터시트

SDS

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