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| 카탈로그 번호 | HA292014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 설명 |
Anti-Human PYCR2 Polyclonal Antibody (HA292014) is a rabbit polyclonal antibody detecting PYCR2 in ELISA, IHC, WB. Suitable for Human.
Highlights
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| 종 반응성 | Human, Mouse, Rat | ||||||||
| 응용 분야 | ELISA, IHC, WB | ||||||||
| 숙주 종 | Rabbit | ||||||||
| 클론성 | Polyclonal | ||||||||
| 이소타입 | IgG | ||||||||
| 면역원 | E. coli - derived recombinant Human PYCR2 (Met1-Lys276). | ||||||||
| 타겟 | Pyrroline-5-carboxylate reductase 2, P5C reductase 2, P5CR 2, 1.5.1.2, PYCR2 | ||||||||
| 정제 | Purified by antigen affinity column. | ||||||||
| 등록번호 | Q96C36 | ||||||||
| 형태 | Liquid | ||||||||
| 저장 완충액 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 배경 | Pyrroline-5-carboxylate reductase 2 (PYCR2) is a ~33 kDa protein. Oxidoreductase that catalyzes the last step in proline biosynthesis, which corresponds to the reduction of pyrroline-5-carboxylate to L-proline using NAD(P)H. At physiologic concentrations, has higher specific activity in the presence of NADH. Involved in cellular response to oxidative stress. In some cell types, such as erythrocytes, its primary function may be the generation of NADP(+). 1. De Ingeniis, J. et al. (2012) PloS one 7, e45190. PMID: 23024808 2. Merrill, MJ. et al. (1989) The Journal of biological chemistry 264, 9352-8. PMID: 2722838 3. Yeh, GC. et al. (1981) The Journal of clinical investigation 67, 1042-6. PMID: 6894153 4. Nakayama, T. et al. (2015) American journal of human genetics 96, 709-19. PMID: 25865492 | ||||||||
| 참고사항 | For research use only. |
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