Anti-Human RAB27A Polyclonal Antibody (HA508014)

Name: Anti-Human RAB27A Polyclonal Antibody
Brand: abinScience
SKU: HA508014
Price: 96 USD
Availability: InStock

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개요
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참고 문헌
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SDS

개요

카탈로그 번호

HA508014

설명

Anti-Human RAB27A Polyclonal Antibody (HA508014) is a rabbit polyclonal antibody detecting RAB27A in ELISA, IHC, WB. Suitable for Rattus norvegicus, Mus musculus, Human, and Sus scrofa.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

종 반응성

Human, Mouse, Rat

응용 분야

ELISA, IHC, WB

숙주 종

Rabbit

클론성

Polyclonal

이소타입

IgG

면역원

E. coli - derived recombinant Human RAB27A (Met1-Lys191).

타겟

RAB27A

정제

Purified by antigen affinity column.

등록번호

P51159

형태

Liquid

저장 완충액

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

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제품 사용 정보

응용 분야	희석
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

안정성 및 저장

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

대체 이름

Ras-related protein Rab-27A, Rab-27, 3.6.5.2, GTP-binding protein Ram, RAB27A, RAB27

배경

Ras-related protein Rab-27A (RAB27A) is a ~24 kDa protein. The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. RAB27A regulates homeostasis of late endocytic pathway, including endosomal positioning, maturation and secretion. Plays a role in cytotoxic granule exocytosis in lymphocytes. Required for both granule maturation and granule docking and priming at the immunologic synapse.

1. Zhang, J. et al. (2019) Biochimica et biophysica acta. Molecular cell research 1866, 916-929. PMID: 30771381

2. Ménasché, G. et al. (2008) Blood 112, 5052-62. PMID: 18812475

참고사항

For research use only.

이미지

참고 문헌

데이터시트

Anti-Human RAB27A Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

재조합 단백질

항체

어세이 키트

Anti-Human RAB27A Polyclonal Antibody (HA508014)

개요

이미지

참고 문헌

데이터시트

SDS