Anti-Human RAB3A Polyclonal Antibody (HB975014)

Name: Anti-Human RAB3A Polyclonal Antibody
Brand: abinScience
SKU: HB975014
Price: 96 USD
Availability: InStock

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개요
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개요

카탈로그 번호

HB975014

설명

Anti-Human RAB3A Polyclonal Antibody (HB975014) is a rabbit polyclonal antibody detecting RAB3A in ELISA, IHC, WB. Suitable for Human.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

종 반응성

Human, Mouse, Rat

응용 분야

ELISA, IHC, WB

숙주 종

Rabbit

클론성

Polyclonal

이소타입

IgG

면역원

E. coli - derived recombinant Human RAB3A (Asp20-Thr193).

타겟

Ras-related protein Rab-3A, RAB3A

정제

Purified by antigen affinity column.

등록번호

P20336

형태

Liquid

저장 완충액

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

제품 사용 정보

응용 분야	희석
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

안정성 및 저장

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

배경

Ras-related protein Rab-3A (RAB3A) is a ~24 kDa protein. The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. RAB3A plays a central role in regulated exocytosis and secretion. Controls the recruitment, tethering and docking of secretory vesicles to the plasma membrane. Upon stimulation, switches to its active GTP-bound form, cycles to vesicles and recruits effectors such as RIMS1, RIMS2, Rabphilin-3A/RPH3A, RPH3AL or SYTL4 to help the docking of vesicules onto the plasma membrane.

1. Zahraoui, A. et al. (1989) The Journal of biological chemistry 264, 12394-401. PMID: 2501306

2. Encarnação, M. et al. (2016) The Journal of cell biology 213, 631-40. PMID: 27325790

3. Bello, OD. et al. (2012) Experimental cell research 318, 478-88. PMID: 22248876

4. Quevedo, MF. et al. (2019) Biochimica et biophysica acta. Molecular cell research 1866, 612-622. PMID: 30599141

참고사항

For research use only.

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참고 문헌

데이터시트

Anti-Human RAB3A Polyclonal Antibody.pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

재조합 단백질

항체

어세이 키트

Anti-Human RAB3A Polyclonal Antibody (HB975014)

개요

이미지

참고 문헌

데이터시트

SDS