Anti-Human RAB3IP Polyclonal Antibody (HP867014)

Name: Anti-Human RAB3IP Polyclonal Antibody
Brand: abinScience
SKU: HP867014
Price: 168 USD
Availability: InStock

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개요
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참고 문헌
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SDS

개요

카탈로그 번호

HP867014

설명

Anti-Human RAB3IP Polyclonal Antibody (HP867014) is a rabbit polyclonal antibody detecting RAB3IP in ELISA, IHC, WB. Suitable for Human.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

종 반응성

Human

응용 분야

ELISA, IHC, WB

숙주 종

Rabbit

클론성

Polyclonal

이소타입

IgG

면역원

E. coli - derived recombinant Human RAB3IP (Asp314-Leu476).

타겟

Rabin-3, Rab3A-interacting protein, Rab-3A-interacting protein, SSX2-interacting protein, RAB3IP, RABIN8

정제

Purified by antigen affinity column.

등록번호

Q96QF0

형태

Liquid

저장 완충액

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

제품 사용 정보

응용 분야	희석
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

안정성 및 저장

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

배경

Rab-3A-interacting protein (RAB3IP) is a ~53 kDa protein. Guanine nucleotide exchange factor (GEF) which may activate RAB8A and RAB8B. Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP-bound form. Mediates the release of GDP from RAB8A and RAB8B but not from RAB3A or RAB5. Modulates actin organization and promotes polarized transport of RAB8A-specific vesicles to the cell surface. Together with RAB11A, RAB8A, the exocyst complex, PARD3, PRKCI, ANXA2, CDC42 and DNMBP promotes transcytosis of PODXL to the apical membrane initiation sites (AMIS), apical surface formation and lumenogenesis.

1. Hattula, K. et al. (2002) Molecular biology of the cell 13, 3268-80. PMID: 12221131

2. Steger, M. et al. (2016) eLife 5. PMID: 26824392

3. Yoshimura, S. et al. (2010) The Journal of cell biology 191, 367-81. PMID: 20937701

4. Bryant, DM. et al. (2010) Nature cell biology 12, 1035-45. PMID: 20890297

5. Wang, J. et al. (2015) Journal of cell science 128, 1375-85. PMID: 25673879

6. Walia, V. et al. (2019) Developmental cell 50, 229-246.e7. PMID: 31204173

참고사항

For research use only.

이미지

참고 문헌

데이터시트

Anti-Human RAB3IP Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

재조합 단백질

항체

어세이 키트

Anti-Human RAB3IP Polyclonal Antibody (HP867014)

개요

이미지

참고 문헌

데이터시트

SDS