

| 카탈로그 번호 | HS824014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 설명 |
Anti-Human RABEP1 Polyclonal Antibody (HS824014) is a rabbit polyclonal antibody detecting RABEP1 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat.
Highlights
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| 종 반응성 | Human, Mouse, Rat | ||||||||
| 응용 분야 | ELISA, IHC, WB | ||||||||
| 숙주 종 | Rabbit | ||||||||
| 클론성 | Polyclonal | ||||||||
| 이소타입 | IgG | ||||||||
| 면역원 | E. coli - derived recombinant Human RABEP1 (Ser464-Glu552). | ||||||||
| 타겟 | RABPT5, RABEP1, Rabaptin-4, RABPT5A, Rab GTPase-binding effector protein 1, Renal carcinoma antigen NY-REN-17, RAB5EP, Rabaptin-5alpha, Rabaptin-5 | ||||||||
| 정제 | Purified by antigen affinity column. | ||||||||
| 등록번호 | Q15276 | ||||||||
| 형태 | Liquid | ||||||||
| 저장 완충액 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 배경 | Rab GTPase-binding effector protein 1 (RABEP1) is a ~99 kDa protein. Rab effector protein acting as linker between gamma-adaptin, RAB4A and RAB5A. Involved in endocytic membrane fusion and membrane trafficking of recycling endosomes. Involved in KCNH1 channels trafficking to and from the cell membrane. Forms a complex with RABGEF1 that stimulates RABGEF1-mediated nucleotide exchange on RAB5A. Mediates the traffic of PKD1:PKD2 complex from the endoplasmic reticulum through the Golgi to the cilium. 1. Ninkovic, M. et al. (2012) FEBS letters 586, 3077-84. PMID: 22841712 2. Horiuchi, H. et al. (1997) Cell 90, 1149-59. PMID: 9323142 | ||||||||
| 참고사항 | For research use only. |
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