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| 카탈로그 번호 | HB122014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 설명 |
Anti-Human RAC2 Polyclonal Antibody (HB122014) is a rabbit polyclonal antibody detecting RAC2 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat.
Highlights
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| 종 반응성 | Human, Mouse, Rat | ||||||||
| 응용 분야 | ELISA, IHC, WB | ||||||||
| 숙주 종 | Rabbit | ||||||||
| 클론성 | Polyclonal | ||||||||
| 이소타입 | IgG | ||||||||
| 면역원 | E. coli - derived recombinant Human RAC2 (Met1-Leu192). | ||||||||
| 타겟 | Small G protein, GX, p21-Rac2, Ras-related C3 botulinum toxin substrate 2, RAC2 | ||||||||
| 정제 | Purified by antigen affinity column. | ||||||||
| 등록번호 | P15153 | ||||||||
| 형태 | Liquid | ||||||||
| 저장 완충액 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 배경 | Ras-related C3 botulinum toxin substrate 2 (RAC2) is a ~21 kDa protein. Plasma membrane-associated small GTPase which cycles between an active GTP-bound and inactive GDP-bound state. In its active state, binds to a variety of effector proteins to regulate cellular responses, such as secretory processes, phagocytose of apoptotic cells and epithelial cell polarization. Regulatory subunit of the phagocyte NADPH oxidase complex that mediates the transfer of electrons from cytosolic NADPH to O2 to produce the superoxide anion (O2(-)). 1. Hsu, AP. et al. (2019) Blood 133, 1977-1988. PMID: 30723080 2. Knaus, UG. et al. (1991) Science (New York, N.Y.) 254, 1512-5. PMID: 1660188 | ||||||||
| 참고사항 | For research use only. |
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