

| 카탈로그 번호 | HY382014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 설명 |
Anti-Human RALB Polyclonal Antibody (HY382014) is a rabbit polyclonal antibody detecting RALB in ELISA, IHC, WB. Suitable for Human.
Highlights
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| 종 반응성 | Human, Mouse, Rat | ||||||||
| 응용 분야 | ELISA, IHC, WB | ||||||||
| 숙주 종 | Rabbit | ||||||||
| 클론성 | Polyclonal | ||||||||
| 이소타입 | IgG | ||||||||
| 면역원 | E. coli - derived recombinant Human RALB (Ser11-Leu206). | ||||||||
| 타겟 | Ras-related protein Ral-B, RALB | ||||||||
| 정제 | Purified by antigen affinity column. | ||||||||
| 등록번호 | P11234 | ||||||||
| 형태 | Liquid | ||||||||
| 저장 완충액 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 배경 | Ras-related protein Ral-B (RALB) is a ~23 kDa protein. Multifunctional GTPase involved in a variety of cellular processes including gene expression, cell migration, cell proliferation, oncogenic transformation and membrane trafficking. Accomplishes its multiple functions by interacting with distinct downstream effectors. Acts as a GTP sensor for GTP-dependent exocytosis of dense core vesicles. Required both to stabilize the assembly of the exocyst complex and to localize functional exocyst complexes to the leading edge of migrating cells. Required for suppression of apoptosis. 1. Nakashima, S. et al. (1999) The EMBO journal 18, 3629-42. PMID: 10393179 2. Falsetti, SC. et al. (2007) Molecular and cellular biology 27, 8003-14. PMID: 17875936 3. Cascone, I. et al. (2008) The EMBO journal 27, 2375-87. PMID: 18756269 | ||||||||
| 참고사항 | For research use only. |

Western blot analysis was performed using anti-RALB polyclonal antibody at 1ug/mL on various samples.
Lane 1: MCF-7 cell lysate
Lane 2: Mouse brain lysate
Lane 3: Mouse lung lysate
Lane 4: Rat brain lysate
Lane 5: Rat lung lysate
Lane 6: Rat kidney lysate


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