Anti-Human RANBP9 Polyclonal Antibody (HP154014)

Name: Anti-Human RANBP9 Polyclonal Antibody
Brand: abinScience
SKU: HP154014
Price: 168 USD
Availability: InStock

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개요
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개요

카탈로그 번호

HP154014

설명

Anti-Human RANBP9 Polyclonal Antibody (HP154014) is a rabbit polyclonal antibody detecting RANBP9 in ELISA, IHC, WB. Suitable for Human, Mouse.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

종 반응성

Human, Mouse

응용 분야

ELISA, IHC, WB

숙주 종

Rabbit

클론성

Polyclonal

이소타입

IgG

면역원

E. coli - derived recombinant Human RANBP9 (Ser176-Gly330).

타겟

RanBP7, RanBPM, RanBP9, Ran-binding protein 9, Ran-binding protein M, BPM90, RANBP9, BPM-L, RANBPM

정제

Purified by antigen affinity column.

등록번호

Q96S59

형태

Liquid

저장 완충액

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

제품 사용 정보

응용 분야	희석
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

안정성 및 저장

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

배경

Ran-binding protein 9 (RANBP9) is a ~77 kDa protein. May act as scaffolding protein, and as adapter protein to couple membrane receptors to intracellular signaling pathways (Probable). Acts as a mediator of cell spreading and actin cytoskeleton rearrangement. Core component of the CTLH E3 ubiquitin-protein ligase complex that selectively accepts ubiquitin from UBE2H and mediates ubiquitination and subsequent proteasomal degradation of the transcription factor HBP1. May be involved in signaling of ITGB2/LFA-1 and other integrins. Enhances HGF-MET signaling by recruiting Sos and activating the Ras pathway.

1. Valiyaveettil, M. et al. (2008) The Journal of cell biology 182, 727-39. PMID: 18710924

2. Lampert, F. et al. (2018) eLife 7. PMID: 29911972

3. Denti, S. et al. (2004) The Journal of biological chemistry 279, 13027-34. PMID: 14722085

4. Wang, D. et al. (2002) The Journal of biological chemistry 277, 36216-22. PMID: 12147692

5. Rao, MA. et al. (2002) The Journal of biological chemistry 277, 48020-7. PMID: 12361945

6. Harada, N. et al. (2008) Biochemical and biophysical research communications 368, 121-5. PMID: 18222118

7. Kramer, S. et al. (2005) Oncogene 24, 938-44. PMID: 15558019

참고사항

For research use only.

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참고 문헌

데이터시트

Anti-Human RANBP9 Polyclonal Antibody.pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

재조합 단백질

항체

어세이 키트

Anti-Human RANBP9 Polyclonal Antibody (HP154014)

개요

이미지

참고 문헌

데이터시트

SDS