

| 카탈로그 번호 | HY078014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 설명 |
Anti-Human RAP2A Polyclonal Antibody (HY078014) is a rabbit polyclonal antibody detecting RAP2A in ELISA, IHC, WB. Suitable for Human.
Highlights
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| 종 반응성 | Human, Mouse, Rat | ||||||||
| 응용 분야 | ELISA, IHC, WB | ||||||||
| 숙주 종 | Rabbit | ||||||||
| 클론성 | Polyclonal | ||||||||
| 이소타입 | IgG | ||||||||
| 면역원 | E. coli - derived recombinant Human RAP2A (Met1-Gln183). | ||||||||
| 타겟 | Ras-related protein Rap-2a, 3.6.5.2, RbBP-30, RAP2A | ||||||||
| 정제 | Purified by antigen affinity column. | ||||||||
| 등록번호 | P10114 | ||||||||
| 형태 | Liquid | ||||||||
| 저장 완충액 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 배경 | Ras-related protein Rap-2a (RAP2A) is a ~20 kDa protein. Small GTP-binding protein which cycles between a GDP-bound inactive and a GTP-bound active form. In its active form interacts with and regulates several effectors including MAP4K4, MINK1 and TNIK. Part of a signaling complex composed of NEDD4, RAP2A and TNIK which regulates neuronal dendrite extension and arborization during development. More generally, it is part of several signaling cascades and regulates cytoskeletal rearrangements, cell migration, cell adhesion and cell spreading. 1. Machida, N. et al. (2004) The Journal of biological chemistry 279, 15711-4. PMID: 14966141 2. Taira, K. et al. (2004) The Journal of biological chemistry 279, 49488-96. PMID: 15342639 3. Mittal, V. et al. (2006) The Biochemical journal 394, 309-15. PMID: 16246175 4. Greco, F. et al. (2006) Biochimica et biophysica acta 1763, 330-5. PMID: 16540189 5. Nonaka, H. et al. (2008) Biochemical and biophysical research communications 377, 573-578. PMID: 18930710 6. Kawabe, H. et al. (2010) Neuron 65, 358-72. PMID: 20159449 7. Duncan, ED. et al. (2022) The Journal of cell biology 221. PMID: 35293963 | ||||||||
| 참고사항 | For research use only. |
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