

| 카탈로그 번호 | HA043014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 설명 |
Anti-Human RCCD1 Polyclonal Antibody (HA043014) is a rabbit polyclonal antibody detecting RCCD1 in ELISA, IHC, WB. Suitable for Human.
Highlights
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| 종 반응성 | Human | ||||||||
| 응용 분야 | ELISA, IHC, WB | ||||||||
| 숙주 종 | Rabbit | ||||||||
| 클론성 | Polyclonal | ||||||||
| 이소타입 | IgG | ||||||||
| 면역원 | E. coli - derived recombinant Human RCCD1 (Met1-Ser376). | ||||||||
| 타겟 | RCC1 domain-containing protein 1, RCCD1 | ||||||||
| 정제 | Purified by antigen affinity column. | ||||||||
| 등록번호 | A6NED2 | ||||||||
| 형태 | Liquid | ||||||||
| 저장 완충액 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 배경 | RCC1 domain-containing protein 1 (RCCD1) is a ~40 kDa protein. Plays a role in transcriptional repression of satellite repeats, possibly by regulating H3K36 methylation levels in centromeric regions together with KDM8. Possibly together with KDM8, is involved in proper mitotic spindle organization and chromosome segregation. Plays a role in regulating alpha-tubulin deacetylation and cytoskeletal microtubule stability, thereby promoting cell migration and TGF-beta-induced epithelial to mesenchymal transition (EMT), potentially through the inhibition of KDM8. 1. Marcon, E. et al. (2014) Cell reports 8, 297-310. PMID: 24981860 2. Wu, J. et al. (2017) Cancer letters 400, 18-29. PMID: 28455245 | ||||||||
| 참고사항 | For research use only. |
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