Anti-Human RCOR1 Polyclonal Antibody (HP659014)

Name: Anti-Human RCOR1 Polyclonal Antibody
Brand: abinScience
SKU: HP659014
Price: 96 USD
Availability: InStock

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개요
이미지
참고 문헌
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SDS

개요

카탈로그 번호

HP659014

설명

Anti-Human RCOR1 Polyclonal Antibody (HP659014) is a rabbit polyclonal antibody detecting RCOR1 in ELISA, IHC, WB. Suitable for Human, Mouse.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

종 반응성

Human, Mouse

응용 분야

ELISA, IHC, WB

숙주 종

Rabbit

클론성

Polyclonal

이소타입

IgG

면역원

E. coli - derived recombinant Human RCOR1 (Asn141-Glu266).

타겟

RCOR1, REST corepressor 1, RCOR, Protein CoREST, KIAA0071

정제

Purified by antigen affinity column.

등록번호

Q9UKL0

형태

Liquid

저장 완충액

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

제품 사용 정보

응용 분야	희석
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

안정성 및 저장

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

배경

REST corepressor 1 (RCOR1) is a ~53 kDa protein. Essential component of the BHC complex, a corepressor complex that represses transcription of neuron-specific genes in non-neuronal cells. The BHC complex is recruited at RE1/NRSE sites by REST and acts by deacetylating and demethylating specific sites on histones, thereby acting as a chromatin modifier. In the BHC complex, it serves as a molecular beacon for the recruitment of molecular machinery, including MeCP2 and SUV39H1, that imposes silencing across a chromosomal interval. Plays a central role in demethylation of Lys-4 of histone H3 by promoting demethylase activity of KDM1A on core histones and nucleosomal substrates. It also protects KDM1A from the proteasome.

참고사항

For research use only.

이미지

Western blot

Western blot analysis was performed using anti-RCOR1 polyclonal antibody at 1μg/ml on various samples.
Lane 1: Molt-4 cell lysate
Lane 2: HT-29 cell lysate
Lane 3: Mouse brain lysate
Lane 4: Mouse testis lysate
Lane 5: Rat brain lysate

참고 문헌

데이터시트

Anti-Human RCOR1 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

재조합 단백질

항체

어세이 키트

Anti-Human RCOR1 Polyclonal Antibody (HP659014)

개요

이미지

참고 문헌

데이터시트

SDS