中文
English
한국어
日本語
Español
Français
Русский
| 카탈로그 번호 | HY021013 | ||||
|---|---|---|---|---|---|
| 종 반응성 | Human | ||||
| 응용 분야 | Blocking, ELISA, ICC | ||||
| 숙주 종 | Mouse | ||||
| 클론성 | Monoclonal | ||||
| 이소타입 | IgG2a, kappa | ||||
| 클론 ID | K42-41L | ||||
| 타겟 | Rhodopsin, OPN2, Opsin-2, RHO | ||||
| 내독소 수준 | Please contact with the lab for this information. | ||||
| 순도 | >95% as determined by SDS-PAGE. | ||||
| 정제 | Protein A/G purified from cell culture supernatant. | ||||
| 등록번호 | P08100 | ||||
| RRID | Anti-Human RHO/Rhodopsin Antibody (K42-41L) (abinScience Cat# HY021013, RRID:AB_3726901) |
||||
| 형태 | Liquid | ||||
| 저장 완충액 | 0.01M PBS pH 7.4 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
||||
| 제품 사용 정보 |
| ||||
| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. | ||||
| 배경 | Rhodopsin is a ~38 kDa protein. Photoreceptor required for image-forming vision at low light intensity. Required for photoreceptor cell viability after birth. Light-induced isomerization of the chromophore 11-cis-retinal to all-trans-retinal triggers a conformational change that activates signaling via G-proteins. Subsequent receptor phosphorylation mediates displacement of the bound G-protein alpha subunit by the arrestin SAG and terminates signaling. _x005F_x005F_x000D_ _x005F_x005F_x000D_1. Sieving, PA. et al. (1995) Proceedings of the National Academy of Sciences of the United States of America 92, 880-4. PMID: 7846071 _x005F_x005F_x000D_
_x005F_x005F_x000D_
2. Rao, VR. et al. (1994) Nature 367, 639-42. PMID: 8107847 _x005F_x005F_x000D_
_x005F_x005F_x000D_
3. Noorwez, SM. et al. (2003) The Journal of biological chemistry 278, 14442-14450. PMID: 12566452 _x005F_x005F_x000D_
_x005F_x005F_x000D_
4. Dryja, TP. et al. (1990) The New England journal of medicine 323, 1302-7. PMID: 2215617 _x005F_x005F_x000D_
_x005F_x005F_x000D_
5. Kang, Y. et al. (2015) Nature 523, 561-7. PMID: 26200343 _x005F_x005F_x000D_
_x005F_x005F_x000D_
6. He, Y. et al. (2017) Cell research 27, 728-747. PMID: 28524165 _x005F_x005F_x000D_
_x005F_x005F_x000D_
7. Zhou, XE. et al. (2017) Cell 170, 457-469.e13. PMID: 28753425 | ||||
| 참고사항 | For research use only. |
SDS-PAGE for Anti-Human RHO/Rhodopsin Antibody (K42-41L)
+86-027-65523339
중국 우한시 심둔사로 666번지 C동, 우한, 430206
