

| 카탈로그 번호 | HP618013 | ||||
|---|---|---|---|---|---|
| 설명 |
Anti-Human RNF43 Recombinant Antibody (SAA1758) (HP618013) is a mouse monoclonal antibody detecting RNF43 in ELISA, WB. Suitable for Human.
Highlights
|
||||
| 종 반응성 | Human | ||||
| 응용 분야 | ELISA, WB | ||||
| 숙주 종 | Mouse | ||||
| 클론성 | Monoclonal | ||||
| 이소타입 | IgG2a, kappa | ||||
| 클론 ID | SAA1758 | ||||
| 타겟 | E3 ubiquitin-protein ligase RNF43, RING finger protein 43, RING-type E3 ubiquitin transferase RNF43, RNF43 | ||||
| 내독소 수준 | Please contact with the lab for this information. | ||||
| 순도 | >95% as determined by SDS-PAGE. | ||||
| 정제 | Protein A/G purified from cell culture supernatant. | ||||
| 등록번호 | Q68DV7 | ||||
| RRID | Anti-Human RNF43 Antibody (SAA1758) (abinScience Cat# HP618013, RRID:AB_3727519) |
||||
| 형태 | Liquid | ||||
| 저장 완충액 | 0.01M PBS pH 7.4 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
||||
| 제품 사용 정보 |
| ||||
| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. | ||||
| 배경 | E3 ubiquitin-protein ligase RNF43 is a ~85 kDa protein. E3 ubiquitin-protein ligase that acts as a negative regulator of the Wnt signaling pathway by mediating the ubiquitination, endocytosis and subsequent degradation of Wnt receptor complex components Frizzled. Acts on both canonical and non-canonical Wnt signaling pathway. Along with RSPO2 and ZNRF3, constitutes a master switch that governs limb specification. 1. Sugiura, T. et al. (2008) Experimental cell research 314, 1519-28. PMID: 18313049 2. Hao, HX. et al. (2012) Nature 485, 195-200. PMID: 22575959 3. Koo, BK. et al. (2012) Nature 488, 665-9. PMID: 22895187 | ||||
| 참고사항 | For research use only. | ||||
| Isotype Control | Mouse IgG2a (Fc Silence) Recombinant Isotype Control (MOPC 173) (MF533023) |

Western blot analysis was performed using anti-mouse RNF43 monoclonal antibody at 1ug/mL on various samples.
Lane 1: ATG11865 200ng
Lane 2: negative control


+86-027-65523339
중국 우한시 심둔사로 666번지 C동, 우한, 430206

中文
English
한국어
日本語
Español
Français
Русский