Anti-Human RNH1 Polyclonal Antibody (HY509014)

Name: Anti-Human RNH1 Polyclonal Antibody
Brand: abinScience
SKU: HY509014
Price: 96 USD
Availability: InStock

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개요
이미지
참고 문헌
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SDS

개요

카탈로그 번호

HY509014

설명

Anti-Human RNH1 Polyclonal Antibody (HY509014) is a rabbit polyclonal antibody detecting RNH1 in ELISA, IHC, WB. Suitable for Human.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

종 반응성

Human

응용 분야

ELISA, IHC, WB

숙주 종

Rabbit

클론성

Polyclonal

이소타입

IgG

면역원

E. coli - derived recombinant Human RNH1 (Asp218-Glu444).

타겟

Ribonuclease inhibitor, Placental ribonuclease inhibitor, Placental RNase inhibitor, Ribonuclease/angiogenin inhibitor 1, RAI, RNH1, PRI, RNH

내독소 수준

Please contact with the lab for this information.

정제

Purified by antigen affinity column.

등록번호

P13489

형태

Liquid

저장 완충액

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

제품 사용 정보

응용 분야	희석
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

안정성 및 저장

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

배경

Ribonuclease inhibitor (RNH1) is a ~49 kDa protein. Ribonuclease inhibitor which inhibits RNASE1, RNASE2 and angiogenin (ANG). May play a role in redox homeostasis. Required to inhibit the cytotoxic tRNA ribonuclease activity of ANG in the cytoplasm in absence of stress. Relocates to the nucleus in response to stress, relieving inhibition of ANG in the cytoplasm, and inhibiting the angiogenic activity of ANG in the nucleus.

1. Teufel, DP. et al. (2003) Biochemistry 42, 1451-9. PMID: 12578357

2. Huang, GH. et al. (2003) Sheng wu hua xue yu sheng wu wu li xue bao Acta biochimica et biophysica Sinica 35, 960-3. PMID: 14515218

3. Lee, FS. et al. (1988) Biochemistry 27, 8545-53. PMID: 3219362

4. Schneider, R. et al. (1988) The EMBO journal 7, 4151-6. PMID: 3243277

5. Shapiro, R. et al. (1987) Proceedings of the National Academy of Sciences of the United States of America 84, 2238-41. PMID: 3470787

6. Chen, CZ. et al. (1997) Proceedings of the National Academy of Sciences of the United States of America 94, 1761-6. PMID: 9050852

7. Monti, DM. et al. (2007) FEBS letters 581, 930-4. PMID: 17292889

8. Pizzo, E. et al. (2013) Journal of cell science 126, 4308-19. PMID: 23843625

9. Bai, R. et al. (2020) The EMBO journal 39, e103325. PMID: 32510170

참고사항

For research use only

이미지

Western blot

Western blot analysis was performed using anti-RNH1 polyclonal antibody at 1ug/mL on various samples.
Lane 1: HepG2 cell lysate
Lane 2: LO2 cell lysate
Lane 3: Jurkat cell lysate
Lane 4: U87 cell lysate
Lane 5: Raji cell lysate

참고 문헌

데이터시트

Anti-Human RNH1 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

재조합 단백질

항체

어세이 키트

Anti-Human RNH1 Polyclonal Antibody (HY509014)

개요

이미지

참고 문헌

데이터시트

SDS