

| 카탈로그 번호 | HB915014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 설명 |
Anti-Human RPS3 Polyclonal Antibody (HB915014) is a rabbit polyclonal antibody detecting RPS3 in ELISA, IHC, WB. Suitable for Ambystoma mexicanum, Bovine, Dog, Human, and Ictalurus punctatus.
Highlights
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| 종 반응성 | Human, Mouse, Rat | ||||||||
| 응용 분야 | ELISA, IHC, WB | ||||||||
| 숙주 종 | Rabbit | ||||||||
| 클론성 | Polyclonal | ||||||||
| 이소타입 | IgG | ||||||||
| 면역원 | E. coli - derived recombinant Human RPS3 (Met1-Lys187). | ||||||||
| 타겟 | Small ribosomal subunit protein uS3, RPS3, 40S ribosomal protein S3 | ||||||||
| 정제 | Purified by antigen affinity column. | ||||||||
| 등록번호 | P23396 | ||||||||
| 형태 | Liquid | ||||||||
| 저장 완충액 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 배경 | Small ribosomal subunit protein uS3 (RPS3) is a ~26 kDa protein. Component of the small ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. Has endonuclease activity and plays a role in repair of damaged DNA. Cleaves phosphodiester bonds of DNAs containing altered bases with broad specificity and cleaves supercoiled DNA more efficiently than relaxed DNA. Displays high binding affinity for 7,8-dihydro-8-oxoguanine (8-oxoG), a common DNA lesion caused by reactive oxygen species (ROS). 1. Anger, AM. et al. (2013) Nature 497, 80-5. PMID: 23636399 2. Vladimirov, SN. et al. (1996) European journal of biochemistry 239, 144-9. PMID: 8706699 3. Kim, J. et al. (1995) The Journal of biological chemistry 270, 13620-9. PMID: 7775413 4. Kim, SH. et al. (2005) Biochemical and biophysical research communications 328, 962-7. PMID: 15707971 5. Hegde, V. et al. (2004) DNA repair 3, 121-6. PMID: 14706345 6. Balyeva, KE. et al. (2008) Molekuliarnaia biologiia 42, 314-22. PMID: 18610840 7. Hegde, V. et al. (2004) Biochemistry 43, 14211-7. PMID: 15518571 8. Ko, SI. et al. (2008) Mutation research 648, 54-64. PMID: 18973764 | ||||||||
| 참고사항 | For research use only. |
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