Anti-Human RRAD Polyclonal Antibody (HD074014)

Name: Anti-Human RRAD Polyclonal Antibody
Brand: abinScience
SKU: HD074014
Price: 168 USD
Availability: InStock

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100ug

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개요
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참고 문헌
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SDS

개요

카탈로그 번호

HD074014

설명

Anti-Human RRAD Polyclonal Antibody (HD074014) is a rabbit polyclonal antibody detecting RRAD. Suitable for Rat, Mouse, and Human.

Highlights

●Multi-Species — Cross-reactive for translational research.

종 반응성

Human, Mouse, Rat

응용 분야

ELISA, IHC, WB

숙주 종

Rabbit

클론성

Polyclonal

이소타입

IgG

면역원

E. coli - derived recombinant Human RRAD (Val91-Leu308).

타겟

GTP-binding protein RAD, RAD, RAD1, RRAD, Ras associated with diabetes

내독소 수준

Please contact with the lab for this information.

정제

Purified by antigen affinity column.

등록번호

P55042

형태

Liquid

저장 완충액

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

제품 사용 정보

응용 분야	희석
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

배경

GTP-binding protein RAD (RRAD) is a ~33 kDa protein. May regulate basal voltage-dependent L-type Ca(2+) currents and be required for beta-adrenergic augmentation of Ca(2+) influx in cardiomyocytes, thereby regulating increases in heart rate and contractile force. May play an important role in cardiac antiarrhythmia via the strong suppression of voltage-gated L-type Ca(2+) currents. Regulates voltage-dependent L-type calcium channel subunit alpha-1C trafficking to the cell membrane. Inhibits cardiac hypertrophy through the calmodulin-dependent kinase II (CaMKII) pathway. Inhibits phosphorylation and activation of CAMK2D.

1. Chang, L. et al. (2007) Circulation 116, 2976-2983. PMID: 18056528

참고사항

For research use only

이미지

참고 문헌

데이터시트

Anti-Human RRAD Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

재조합 단백질

항체

어세이 키트

Anti-Human RRAD Polyclonal Antibody (HD074014)

개요

이미지

참고 문헌

데이터시트

SDS