Anti-Human RUBCN Polyclonal Antibody (HA317014)

Name: Anti-Human RUBCN Polyclonal Antibody
Brand: abinScience
SKU: HA317014
Price: 96 USD
Availability: InStock

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개요
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참고 문헌
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SDS

개요

카탈로그 번호

HA317014

설명

Anti-Human RUBCN Polyclonal Antibody (HA317014) is a rabbit polyclonal antibody detecting RUBCN in ELISA, IHC, WB. Suitable for Human.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

종 반응성

Human, Mouse

응용 분야

ELISA, IHC, WB

숙주 종

Rabbit

클론성

Polyclonal

이소타입

IgG

면역원

E. coli - derived recombinant Human RUBCN (Arg710-Thr972).

타겟

RUBCN, KIAA0226, Beclin-1 associated RUN domain containing protein, Rubicon, Baron, Run domain Beclin-1-interacting and cysteine-rich domain-containing protein

정제

Purified by antigen affinity column.

등록번호

Q92622

형태

Liquid

저장 완충액

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

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제품 사용 정보

응용 분야	희석
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

안정성 및 저장

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

배경

Run domain Beclin-1-interacting and cysteine-rich domain-containing protein (RUBCN) is a ~108 kDa protein. Inhibits PIK3C3 activity; under basal conditions negatively regulates PI3K complex II (PI3KC3-C2) function in autophagy. Negatively regulates endosome maturation and degradative endocytic trafficking and impairs autophagosome maturation process. Can sequester UVRAG from association with a class C Vps complex (possibly the HOPS complex) and negatively regulates Rab7 activation.

1. Sun, Q. et al. (2010) Proceedings of the National Academy of Sciences of the United States of America 107, 19338-43. PMID: 20974968

2. Sun, Q. et al. (2011) The Journal of biological chemistry 286, 185-91. PMID: 21062745

참고사항

For research use only.

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참고 문헌

데이터시트

Anti-Human RUBCN Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

재조합 단백질

항체

어세이 키트

Anti-Human RUBCN Polyclonal Antibody (HA317014)

개요

이미지

참고 문헌

데이터시트

SDS