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| 카탈로그 번호 | HY256013 | ||||
|---|---|---|---|---|---|
| 종 반응성 | Human | ||||
| 응용 분야 | ELISA | ||||
| 숙주 종 | Mouse | ||||
| 클론성 | Monoclonal | ||||
| 이소타입 | IgG2a, kappa | ||||
| 클론 ID | SAA1555 | ||||
| 타겟 | S100 calcium-binding protein B, S100B, S-100 protein subunit beta, Protein S100-B, S-100 protein beta chain | ||||
| 내독소 수준 | Please contact with the lab for this information. | ||||
| 순도 | >95% as determined by SDS-PAGE. | ||||
| 정제 | Protein A/G purified from cell culture supernatant. | ||||
| 등록번호 | P04271 | ||||
| RRID | Anti-Human S100B Antibody (SAA1555) (abinScience Cat# HY256013, RRID:AB_3727316) |
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| 형태 | Liquid | ||||
| 저장 완충액 | 0.01M PBS pH 7.4 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. | ||||
| 배경 | Protein S100-B (S100B) is a ~10 kDa protein. Small zinc- and- and calcium-binding protein that is highly expressed in astrocytes and constitutes one of the most abundant soluble proteins in brain. Weakly binds calcium but binds zinc very tightly-distinct binding sites with different affinities exist for both ions on each monomer. Physiological concentrations of potassium ion antagonize the binding of both divalent cations, especially affecting high-affinity calcium-binding sites. Acts as a neurotrophic factor that promotes astrocytosis and axonal proliferation. Involved in innervation of thermogenic adipose tissue by acting as an adipocyte-derived neurotrophic factor that promotes sympathetic innervation of adipose tissue. 1. Ostendorp, T. et al. (2011) Biochimica et biophysica acta 1813, 1083-91. PMID: 20950652 2. Baudier, J. et al. (1984) Biochimica et biophysica acta 790, 164-73. PMID: 6487634 3. Gilquin, B. et al. (2010) Molecular and cellular biology 30, 2724-36. PMID: 20351179 4. Yamaguchi, F. et al. (2012) The Journal of biological chemistry 287, 13787-98. PMID: 22399290 | ||||
| 참고사항 | For research use only. |
SDS-PAGE for Anti-Human S100B Antibody (SAA1555)
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