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Anti-Human SCARB1/SR-BI/CLA-1/SRB1 Polyclonal Antibody (HP511014)

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개요
카탈로그 번호HP511014
설명
Anti-Human SCARB1/SR-BI/CLA-1/SRB1 Polyclonal Antibody (HP511014) is a rabbit polyclonal antibody detecting SR-BI in ELISA, IHC, WB. Suitable for Human, Pig, Dog, and Cat.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
  • ●Multi-Species — Cross-reactive for translational research.
종 반응성Human
응용 분야ELISA, IHC, WB
숙주 종Rabbit
클론성Polyclonal
이소타입IgG
면역원 E. coli - derived recombinant Human SCARB1/SR-BI/CLA-1/SRB1 (Ile61-Gly424).
타겟 Scavenger receptor class B member 1, SRB1, CD36 and LIMPII analogous 1, CLA-1, CD36 antigen-like 1, Collagen type I receptor, thrombospondin receptor-like 1, SR-BI, CD36, SCARB1, CD36L1, CLA1
내독소 수준 Please contact with the lab for this information.
정제 Purified by antigen affinity column.
등록번호 Q8WTV0, Q8SQC1
형태 Liquid
저장 완충액 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

제품 사용 정보
응용 분야 희석
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
안정성 및 저장 Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
배경

Scavenger receptor class B member 1 (SCARB1/SR-BI) is a ~60 kDa protein. Receptor for different ligands such as phospholipids, cholesterol ester, lipoproteins, phosphatidylserine and apoptotic cells. Receptor for HDL, mediating selective uptake of cholesteryl ether and HDL-dependent cholesterol efflux. Also facilitates the flux of free and esterified cholesterol between the cell surface and apoB-containing lipoproteins and modified lipoproteins, although less efficiently than HDL. May be involved in the phagocytosis of apoptotic cells, via its phosphatidylserine binding activity.

1. Kawasaki, Y. et al. (2002) The Journal of biological chemistry 277, 27559-66. PMID: 12016218
2. Tai, ES. et al. (2003) Clinical genetics 63, 53-8. PMID: 12519372
3. Vergeer, M. et al. (2011) The New England journal of medicine 364, 136-45. PMID: 21226579
4. Zanoni, P. et al. (2016) Science (New York, N.Y.) 351, 1166-71. PMID: 26965621
참고사항 For research use only.
이미지
참고 문헌
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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