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Anti-Human SCNN1D Polyclonal Antibody (HD658014)

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개요
카탈로그 번호HD658014
설명
Anti-Human SCNN1D Polyclonal Antibody (HD658014) is a rabbit polyclonal antibody detecting SCNN1D. Suitable for Human.
종 반응성Human
응용 분야ELISA, IHC, WB
숙주 종Rabbit
클론성Polyclonal
이소타입IgG
면역원 E. coli - derived recombinant Human SCNN1D (Arg277-Tyr683).
타겟 Amiloride-sensitive sodium channel subunit delta, DNACH, Delta-ENaC, Delta-NaCH, ENaCD, Epithelial Na(+) channel subunit delta, Epithelial sodium channel subunit delta, Nonvoltage-gated sodium channel 1 subunit delta, SCNED, SCNN1D
내독소 수준 Please contact with the lab for this information.
정제 Purified by antigen affinity column.
등록번호 P51172
형태 Liquid
저장 완충액 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

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제품 사용 정보
응용 분야 희석
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
배경

Epithelial sodium channel subunit delta (SCNN1D) is a ~87 kDa protein. Potential alternative pore-forming subunit of the epithelial sodium channel (ENaC), capable of replacing the alpha/SCNN1A subunit, creating a more active channel with distinct properties. ENaC functions in epithelial tissues, where it facilitates the electrodiffusion of sodium ions from the extracellular fluid through the apical membrane of cells, with water following osmotically, regulating sodium balance and fluid homeostasis. This subunit could also function independently as a sodium channel or assemble into other tissue-specific heterotrimeric sodium channels.

1. Ji, HL. et al. (2006) The Journal of biological chemistry 281, 8233-41. PMID: 16423824
2. Bangel-Ruland, N. et al. (2010) American journal of respiratory cell and molecular biology 42, 498-505. PMID: 19520916
3. Zhao, RZ. et al. (2012) American journal of physiology. Lung cellular and molecular physiology 302, L1262-72. PMID: 22505667
4. Waldmann, R. et al. (1995) The Journal of biological chemistry 270, 27411-4. PMID: 7499195
참고사항 For research use only
이미지
참고 문헌
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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