Anti-Human SENP3 Polyclonal Antibody (HP948014)

Name: Anti-Human SENP3 Polyclonal Antibody
Brand: abinScience
SKU: HP948014
Price: 168 USD
Availability: InStock

데이터시트 제품 공유 정보 복사

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사양:

50ug
100ug

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개요
이미지
참고 문헌
데이터시트
SDS

개요

카탈로그 번호

HP948014

종 반응성

Human, Mouse

응용 분야

ELISA, IHC, WB

숙주 종

Rabbit

클론성

Polyclonal

이소타입

IgG

면역원

E. coli - derived recombinant Human SENP3 (Glu311-Val574).

타겟

Sentrin-specific protease 3, Sentrin/SUMO-specific protease SENP3, SENP3, SUSP3, SUMO-1-specific protease 3, SSP3

정제

Purified by antigen affinity column.

등록번호

Q9H4L4

형태

Liquid

저장 완충액

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

제품 사용 정보

응용 분야	희석
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

안정성 및 저장

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

배경

Sentrin-specific protease 3 (SENP3) is a ~65 kDa protein. Protease that releases SUMO2 and SUMO3 monomers from sumoylated substrates, but has only weak activity against SUMO1 conjugates. Deconjugates SUMO2 from MEF2D, which increases its transcriptional activation capability. Deconjugates SUMO2 and SUMO3 from CDCA8. Redox sensor that, when redistributed into nucleoplasm, can act as an effector to enhance HIF1A transcriptional activity by desumoylating EP300. Required for rRNA processing through deconjugation of SUMO2 and SUMO3 from nucleophosmin, NPM1.

1. Gong, L. et al. (2006) The Journal of biological chemistry 281, 15869-77. PMID: 16608850

2. Gao, SS. et al. (2020) Science advances 6, eaba7822. PMID: 32832608

3. Zhang, T. et al. (2022) Nature communications 13, 5133. PMID: 36050397

4. Grégoire, S. et al. (2005) Molecular and cellular biology 25, 2273-87. PMID: 15743823

5. Klein, UR. et al. (2009) Molecular biology of the cell 20, 410-8. PMID: 18946085

6. Huang, C. et al. (2009) The EMBO journal 28, 2748-62. PMID: 19680224

7. Yun, C. et al. (2008) The Journal of cell biology 183, 589-95. PMID: 19015314

8. Haindl, M. et al. (2008) EMBO reports 9, 273-9. PMID: 18259216

9. Fanis, P. et al. (2012) Molecular & cellular proteomics : MCP 11, 1263-73. PMID: 22872859

참고사항

For research use only.

이미지

참고 문헌

데이터시트

Anti-Human SENP3 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

재조합 단백질

항체

어세이 키트

Anti-Human SENP3 Polyclonal Antibody (HP948014)

개요

이미지

참고 문헌

데이터시트

SDS

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