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| 카탈로그 번호 | HP266013 | ||||
|---|---|---|---|---|---|
| 종 반응성 | Human | ||||
| 응용 분야 | ELISA, IF, IP | ||||
| 숙주 종 | Mouse | ||||
| 클론성 | Monoclonal | ||||
| 이소타입 | IgG2a, kappa | ||||
| 클론 ID | SAA0222 | ||||
| 타겟 | hSETD3, SETD3, Actin-histidine N-methyltransferase, SET domain-containing protein 3, C14orf154 | ||||
| 내독소 수준 | Please contact with the lab for this information. | ||||
| 순도 | >95% as determined by SDS-PAGE. | ||||
| 정제 | Protein A/G purified from cell culture supernatant. | ||||
| 등록번호 | Q86TU7 | ||||
| RRID | Anti-Human SETD3 IP Antibody (SAA0222) (abinScience Cat# HP266013, RRID:AB_3729756) |
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| 형태 | Liquid | ||||
| 저장 완충액 | 0.01M PBS pH 7.4 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. | ||||
| 배경 | Actin-histidine N-methyltransferase (SETD3) is a ~67 kDa protein. Protein-histidine N-methyltransferase that specifically mediates 3-methylhistidine (tele-methylhistidine) methylation of actin at 'His-73'. Histidine methylation of actin is required for smooth muscle contraction of the laboring uterus during delivery. Does not have protein-lysine N-methyltransferase activity and probably only catalyzes histidine methylation of actin. 1. Kwiatkowski, S. et al. (2018) eLife 7. PMID: 30526847 2. Wilkinson, AW. et al. (2019) Nature 565, 372-376. PMID: 30626964 3. Guo, Q. et al. (2019) eLife 8. PMID: 30785395 4. Dai, S. et al. (2019) Nature communications 10, 3541. PMID: 31388018 5. Zheng, Y. et al. (2020) Cell discovery 6, 3. PMID: 31993215 | ||||
| 참고사항 | For research use only. |
SDS-PAGE for Anti-Human SETD3 IP Antibody (SAA0222)
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