Anti-Human SH3BP5 Polyclonal Antibody (HT138014)

Name: Anti-Human SH3BP5 Polyclonal Antibody
Brand: abinScience
SKU: HT138014
Price: 168 USD
Availability: InStock

데이터시트 제품 공유 정보 복사

가격(USD): --

사양:

50ug
100ug

수량:

문의하기

개요
이미지
참고 문헌
데이터시트
SDS

개요

카탈로그 번호

HT138014

설명

Anti-Human SH3BP5 Polyclonal Antibody (HT138014) is a rabbit polyclonal antibody detecting SH3BP5 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

종 반응성

Human, Mouse, Rat

응용 분야

ELISA, IHC, WB

숙주 종

Rabbit

클론성

Polyclonal

이소타입

IgG

면역원

E. coli - derived recombinant Human SH3BP5 (Ser10-Glu276).

타겟

SAB, SH3 domain-binding protein that preferentially associates with BTK, SH3 domain-binding protein 5, SH3BP5, SH3BP-5

정제

Purified by antigen affinity column.

등록번호

O60239

형태

Liquid

저장 완충액

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

제품 사용 정보

응용 분야	희석
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

안정성 및 저장

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

배경

SH3 domain-binding protein 5 (SH3BP5) is a ~50 kDa protein. Functions as a guanine nucleotide exchange factor (GEF) with specificity for RAB11A and RAB25. Inhibits the auto- and transphosphorylation activity of BTK. Plays a negative regulatory role in BTK-related cytoplasmic signaling in B-cells. May be involved in BCR-induced apoptotic cell death.

1. Sakaguchi, A. et al. (2015) Developmental cell 35, 211-21. PMID: 26506309

2. Jenkins, ML. et al. (2018) Nature communications 9, 3772. PMID: 30217979

참고사항

For research use only.

이미지

참고 문헌

데이터시트

Anti-Human SH3BP5 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

재조합 단백질

항체

어세이 키트

Anti-Human SH3BP5 Polyclonal Antibody (HT138014)

개요

이미지

참고 문헌

데이터시트

SDS