Anti-Human SIRT3 Polyclonal Antibody (HP409014)

Name: Anti-Human SIRT3 Polyclonal Antibody
Brand: abinScience
SKU: HP409014
Price: 168 USD
Availability: InStock

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개요
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개요

카탈로그 번호

HP409014

설명

Anti-Human SIRT3 Polyclonal Antibody (HP409014) is a rabbit polyclonal antibody detecting SIRT3 in ELISA, IHC, WB. Suitable for Human.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

종 반응성

Human

응용 분야

ELISA, IHC, WB

숙주 종

Rabbit

클론성

Polyclonal

이소타입

IgG

면역원

E. coli - derived recombinant Human SIRT3 (Lys122-Lys399).

타겟

NAD-dependent protein deacetylase sirtuin-3, mitochondrial, SIR2-like protein 3, SIRT3, Regulatory protein SIR2 homolog 3, SIR2L3, hSIRT3

정제

Purified by antigen affinity column.

등록번호

Q9NTG7

형태

Liquid

저장 완충액

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

제품 사용 정보

응용 분야	희석
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

안정성 및 저장

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

배경

NAD-dependent protein deacetylase sirtuin-3, mitochondrial (SIRT3) is a ~43 kDa protein. NAD-dependent protein deacetylase. Activates or deactivates mitochondrial target proteins by deacetylating key lysine residues. Known targets include ACSS1, IDH, GDH, SOD2, PDHA1, LCAD, SDHA, MRPL12 and the ATP synthase subunit ATP5PO. Contributes to the regulation of the cellular energy metabolism. Important for regulating tissue-specific ATP levels.

1. Schwer, B. et al. (2002) The Journal of cell biology 158, 647-57. PMID: 12186850

2. Onyango, P. et al. (2002) Proceedings of the National Academy of Sciences of the United States of America 99, 13653-8. PMID: 12374852

3. Schwer, B. et al. (2006) Proceedings of the National Academy of Sciences of the United States of America 103, 10224-10229. PMID: 16788062

4. Schlicker, C. et al. (2008) Journal of molecular biology 382, 790-801. PMID: 18680753

5. Ahn, BH. et al. (2008) Proceedings of the National Academy of Sciences of the United States of America 105, 14447-52. PMID: 18794531

6. Jin, L. et al. (2009) The Journal of biological chemistry 284, 24394-405. PMID: 19535340

7. Peserico, A. et al. (2013) Cellular and molecular life sciences : CMLS 70, 2015-29. PMID: 23283301

8. Bharathi, SS. et al. (2013) The Journal of biological chemistry 288, 33837-33847. PMID: 24121500

9. Vassilopoulos, A. et al. (2014) Antioxidants & redox signaling 21, 551-64. PMID: 24252090

참고사항

For research use only.

이미지

참고 문헌

데이터시트

Anti-Human SIRT3 Polyclonal Antibody.pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

재조합 단백질

항체

어세이 키트

Anti-Human SIRT3 Polyclonal Antibody (HP409014)

개요

이미지

참고 문헌

데이터시트

SDS