

| 카탈로그 번호 | HA515014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 설명 |
Anti-Human SIX1 Polyclonal Antibody (HA515014) is a rabbit polyclonal antibody detecting SIX1 in ELISA, IHC, WB. Suitable for Mus musculus, Danio rerio, Human, and Xenopus laevis.
Highlights
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| 종 반응성 | Human, Mouse | ||||||||
| 응용 분야 | ELISA, IHC, WB | ||||||||
| 숙주 종 | Rabbit | ||||||||
| 클론성 | Polyclonal | ||||||||
| 이소타입 | IgG | ||||||||
| 면역원 | E. coli - derived recombinant Human SIX1 (Met1-Lys199). | ||||||||
| 타겟 | SIX1 | ||||||||
| 정제 | Purified by antigen affinity column. | ||||||||
| 등록번호 | Q15475 | ||||||||
| 형태 | Liquid | ||||||||
| 저장 완충액 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 대체 이름 | Homeobox protein SIX1, Sine oculis homeobox homolog 1, SIX1 | ||||||||
| 배경 | Homeobox protein SIX1 is a ~32 kDa protein. Transcription factor that is involved in the regulation of cell proliferation, apoptosis and embryonic development. Plays an important role in the development of several organs, including kidney, muscle and inner ear. Depending on context, functions as a transcriptional repressor or activator. Lacks an activation domain, and requires interaction with EYA family members for transcription activation. Mediates nuclear translocation of EYA1 and EYA2. 1. Ruf, RG. et al. (2004) Proceedings of the National Academy of Sciences of the United States of America 101, 8090-5. PMID: 15141091 2. Patrick, AN. et al. (2009) The Journal of biological chemistry 284, 20781-90. PMID: 19497856 3. Patrick, AN. et al. (2013) Nature structural & molecular biology 20, 447-53. PMID: 23435380 4. Brunmeir, R. et al. (2016) PLoS genetics 12, e1006474. PMID: 27923061 5. Coletta, RD. et al. (2004) Proceedings of the National Academy of Sciences of the United States of America 101, 6478-83. PMID: 15123840 | ||||||||
| 참고사항 | For research use only. |

Western blot analysis was performed using anti-SIX1 polyclonal antibody at 1ug/mL on various samples.
Lane 1: Mouse skeletal muscle lysate


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