Anti-Human SLC10A2 Polyclonal Antibody (HC032014)

Name: Anti-Human SLC10A2 Polyclonal Antibody
Brand: abinScience
SKU: HC032014
Price: 96 USD
Availability: InStock

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개요
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참고 문헌
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SDS

개요

카탈로그 번호

HC032014

설명

Anti-Human SLC10A2 Polyclonal Antibody (HC032014) is a rabbit polyclonal antibody detecting ileal; Solute carrier family 10 member 2; SLC10A2; ASBT; ISBT; NTCP2 in ELISA, IHC, WB. Suitable for Human.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

종 반응성

Human

응용 분야

ELISA, IHC, WB

숙주 종

Rabbit

클론성

Polyclonal

이소타입

IgG

면역원

E. coli - derived recombinant human SLC10A2 (Asn2-Asn28&Gly104-Ser126&Arg246-Asn284&Gly306-Lys348).

타겟

Ileal sodium/bile acid cotransporter; Apical sodium-dependent bile acid transporter; ASBT; Ileal Na(+)/bile acid cotransporter; Ileal sodium-dependent bile acid transporter; IBAT; ISBT; Na(+)-dependent ileal bile acid transporter; Sodium/taurocholate cotransporting polypeptide, ileal; Solute carrier family 10 member 2; SLC10A2; ASBT; ISBT; NTCP2

내독소 수준

Please contact with the lab for this information.

정제

Purified by antigen affinity column.

등록번호

Q12908

형태

Liquid

저장 완충액

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

제품 사용 정보

응용 분야	희석
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

안정성 및 저장

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

배경

Ileal sodium/bile acid cotransporter (SLC10A2) is a ~37 kDa protein. Plays a critical role in the sodium-dependent reabsorption of bile acids from the lumen of the small intestine. Transports various bile acids, unconjugated or conjugated, such as cholate and taurocholate. Also responsible for bile acid transport in the renal proximal tubules, a salvage mechanism that helps conserve bile acids (Probable). Works collaboratively with the Na(+)-taurocholate cotransporting polypeptide (NTCP), the organic solute transporter (OST), and the bile salt export pump (BSEP), to ensure efficacious biological recycling of bile acids during enterohepatic circulation.

1. Wong, MH. et al. (1995) The Journal of biological chemistry 270, 27228-34. PMID: 7592981

2. Craddock, AL. et al. (1998) The American journal of physiology 274, G157-69. PMID: 9458785

3. Weinman, SA. et al. (1998) The Journal of biological chemistry 273, 34691-5. PMID: 9856990

4. Kunst, RF. et al. (2021) Hepatology (Baltimore, Md.) 73, 2577-2585. PMID: 33222321

참고사항

For research use only

이미지

참고 문헌

데이터시트

Anti-Human SLC10A2 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

재조합 단백질

항체

어세이 키트

Anti-Human SLC10A2 Polyclonal Antibody (HC032014)

개요

이미지

참고 문헌

데이터시트

SDS