Anti-Human SLC1A5 Recombinant Antibody (SAA0181), APC (HS734137)

Name: Anti-Human SLC1A5 Recombinant Antibody (SAA0181), APC
Brand: abinScience
SKU: HS734137
Price: 290 USD
Availability: InStock

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개요
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개요

카탈로그 번호	HS734137
종 반응성	Human
응용 분야	FCM
숙주 종	Human
클론성	Monoclonal
이소타입	IgG1, kappa
클론 ID	SAA0181
접합	APC
타겟	Baboon M7 virus receptor, SLC1A5, Solute carrier family 1 member 5, ASCT2, RDR, RD114/simian type D retrovirus receptor, Sodium-dependent neutral amino acid transporter type 2, ATB(0), Neutral amino acid transporter B(0), M7V1, RDRC
내독소 수준	Please contact with the lab for this information.
관련 제품	Human IgG1 Recombinant Isotype Control Antibody (HyHEL-10), APC
등록번호	Q15758
형태	Liquid
저장 완충액	0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.
안정성 및 저장	Store at 4°C for 12 months. Protect from light. Do not freeze.
배경	Neutral amino acid transporter B(0) (SLC1A5) is a ~56 kDa protein. Sodium-coupled antiporter of neutral amino acids. In a tri-substrate transport cycle, exchanges neutral amino acids between the extracellular and intracellular compartments, coupled to the inward cotransport of at least one sodium ion. The preferred substrate is the essential amino acid L-glutamine, a precursor for biosynthesis of proteins, nucleotides and amine sugars as well as an alternative fuel for mitochondrial oxidative phosphorylation. Exchanges L-glutamine with other neutral amino acids such as L-serine, L-threonine and L-asparagine in a bidirectional way. Provides L-glutamine to proliferating stem and activated cells driving the metabolic switch toward cell differentiation. 1. Dun, Y. et al. (2007) Experimental eye research 84, 191-9. PMID: 17094966 2. Pingitore, P. et al. (2013) Biochimica et biophysica acta 1828, 2238-46. PMID: 23756778 3. Scalise, M. et al. (2015) FEBS letters 589, 3617-23. PMID: 26492990 4. Garaeva, AA. et al. (2018) Nature structural & molecular biology 25, 515-521. PMID: 29872227 5. Mazza, T. et al. (2021) FEBS letters 595, 3030-3041. PMID: 34741534 6. Kekuda, R. et al. (1996) The Journal of biological chemistry 271, 18657-61. PMID: 8702519 7. Borowska, AM. et al. (2024) Nature communications 15, 6570. PMID: 39095408 8. Foster, AC. et al. (2016) PloS one 11, e0156551. PMID: 27272177 9. Oburoglu, L. et al. (2014) Cell stem cell 15, 169-84. PMID: 24953180
참고사항	For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only.

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Flow CytoMetry

Flow-cytometry using APC anti-human SLC1A5 antibody. Jurkat cells were stained with an irrelevant antibody (Blue Histogram) or an APC anti-human SLC1A5 monoclonal antibody (Catalog: HS734137, Yellow Histogram) at a concentration of 5 µg/ml for 30 mins at RT. After washing, and cells analysed on a NovoCyte Flow Cytometer.

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